Protein Alignment Nmda1 and TMBIM4

DIOPT Version :9

• Sequence 1: NP_523722.1
• Gene: Nmda1 / 36419
• FlyBaseID: FBgn0013305
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_001269535.1
• Gene: TMBIM4 / 51643
• HGNCID: 24257
• Length: 285
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 80/229 - (34%)
• Similarity: 123/229 - (53%)
• Gaps: 26/229 - (11%)

  Fly   107 QSIRRG----------FIRKVYLILMGQLIVTFGAVALFVYHEGTKTFARNNMWLFWV----ALG 157
            ||.|.|          |:||||.||..|:::|.....:|:|.|..:||...:..|..:    :||
Human    65 QSGRSGMVNIFYKGPTFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLG 129

  Fly   158 VMLVTMLSMACCESVRRQTPTNFIFLGLFTAAQSFLMGVSATKYAPKEVLMAVGITAAVCLALTI 222
            ::...:|:       |.:.|.|...|..||..::..:.|..|.|....:|.|..:|..|...||:
Human   130 LIFALILN-------RHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTV 187

  Fly   223 FALQTKYDFTMMGGILIACMVVFLIFGIVAIFVKGKIITLVYASIGALLFSVYLIYDTQLMMGGE 287
            :.||:|.||:..|..|.|.:.:..:.|.:..|...:|:.||.|:.|||||..::||||..:|
Human   188 YTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLM--- 249

  Fly   288 HKYSISPEEYIFAALNLYLDIINIFMYILTIIGA 321
            ||  :|||||:.||::|||||||:|:::|..:.|
Human   250 HK--LSPEEYVLAAISLYLDIINLFLHLLRFLEA 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	79/226 (35%)
TMBIM4	NP_001269535.1	GAAP_like	6..283	CDD:198411	80/229 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.760