Protein Alignment Nmda1 and GRINA

DIOPT Version :9

• Sequence 1: NP_523722.1
• Gene: Nmda1 / 36419
• FlyBaseID: FBgn0013305
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_000828.1
• Gene: GRINA / 2907
• HGNCID: 4589
• Length: 371
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 154/328 - (46%)
• Similarity: 212/328 - (64%)
• Gaps: 21/328 - (6%)

  Fly     7 PQYPQYQDPNQQYNYGGGNPPQGGYGGYPPQGGYPPQGPPQGYPPYAQGGAQPYPQ-PYGQGP-P 69
            |.||....|..|..|..|..|||||    |||.||.:|.|||  ||.|||   ||| ||.|.| |
Human    55 PGYPHGPSPYPQGGYPQGPYPQGGY----PQGPYPQEGYPQG--PYPQGG---YPQGPYPQSPFP 110

  Fly    70 PGGYA-PQ--PGFIQPPPSAGGY-----GAYDDPESQPKNFSFDDQSIRRGFIRKVYLILMGQLI 126
            |..|. ||  ||.....|..|.|     .:|.|.:..|.. ::||:|||:.|||||:|:|..||.
Human   111 PNPYGQPQVFPGQDPDSPQHGNYQEEGPPSYYDNQDFPAT-NWDDKSIRQAFIRKVFLVLTLQLS 174

  Fly   127 VTFGAVALFVYHEGTKTFARNNMWLFWVALGVMLVTMLSMACCESVRRQTPTNFIFLGLFTAAQS 191
            ||...|::|.:....|.|.|.|:|.::|:..|..::::.::||...||:.|.|.:.|.:.||:.|
Human   175 VTLSTVSVFTFVAEVKGFVRENVWTYYVSYAVFFISLIVLSCCGDFRRKHPWNLVALSVLTASLS 239

  Fly   192 FLMGVSATKYAPKEVLMAVGITAAVCLALTIFALQTKYDFTMMGGILIACMVVFLIFGIVAIFVK 256
            :::|:.|:.|..:.|:||||||.|||..:.||::||:||||...|:|:..|||..||.|:.||::
Human   240 YMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSMVVLFIFAILCIFIR 304

  Fly   257 GKIITLVYASIGALLFSVYLIYDTQLMMGGEHKYSISPEEYIFAALNLYLDIINIFMYILTIIGA 321
            .:|:.:||||:|||||:.:|..||||::|.: :.|:|||||:|||||||.||||||:|||||||.
Human   305 NRILEIVYASLGALLFTCFLAVDTQLLLGNK-QLSLSPEEYVFAALNLYTDIINIFLYILTIIGR 368

  Fly   322 SRD 324
            :::
Human   369 AKE 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	106/216 (49%)
GRINA	NP_000828.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..145		45/98 (46%)
		Pro-rich	<43..139	CDD:373673	43/92 (47%)
		LFG_like	151..367	CDD:198410	106/216 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	213	1.000	Domainoid score	I2749
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41517
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2918
Isobase	1	0.950	-	0	Normalized mean entropy	S1892
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm8436
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.760