DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmda1 and Grina

DIOPT Version :9

Sequence 1:	NP_523722.1	Gene:	Nmda1 / 36419	FlyBaseID:	FBgn0013305	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_695220.4	Gene:	Grina / 266668	RGDID:	628873	Length:	348	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	150/329 - (45%)
Similarity:	210/329 - (63%)	Gaps:	35/329 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YPQ-------YQDPNQQYNYGGGNPPQGGYGGYPPQGGYPPQGPPQGYPPYAQGGAQPY-PQPYG 65
            |||       |..|.  |.:|.|..|||||    |||.||..|.|||  ||.|   .|: |.|||
  Rat    42 YPQAAFQPSPYGQPG--YPHGPGPYPQGGY----PQGPYPQGGYPQG--PYPQ---SPFPPNPYG 95

  Fly    66 QGPP---PGGYAPQPGFIQP--PPSAGGYGAYDDPESQPKNFSFDDQSIRRGFIRKVYLILMGQL 125
            |.||   ||  :||.|..|.  |||     .||:.:....|:   |:|||:.|||||:|:|..||
  Rat    96 QPPPFQDPG--SPQHGNYQEEGPPS-----YYDNQDFPSVNW---DKSIRQAFIRKVFLVLTLQL 150

  Fly   126 IVTFGAVALFVYHEGTKTFARNNMWLFWVALGVMLVTMLSMACCESVRRQTPTNFIFLGLFTAAQ 190
            .||...||:|.:....|.|.|.|:|.::|:..:..::::.::||...||:.|.|.:.|.:.|.:.
  Rat   151 SVTLSTVAIFTFVGEVKGFVRANVWTYYVSYAIFFISLIVLSCCGDFRRKHPWNLVALSILTISL 215

  Fly   191 SFLMGVSATKYAPKEVLMAVGITAAVCLALTIFALQTKYDFTMMGGILIACMVVFLIFGIVAIFV 255
            |:::|:.|:.|..:.|:||||||.|||..:.||::||:||||...|:|:..:||..||.|:.||:
  Rat   216 SYMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSVVVLFIFAILCIFI 280

  Fly   256 KGKIITLVYASIGALLFSVYLIYDTQLMMGGEHKYSISPEEYIFAALNLYLDIINIFMYILTIIG 320
            :.:|:.:||||:|||||:.:|..||||::|.: :.|:|||||:|||||||.||||||:|||||||
  Rat   281 RNRILEIVYASLGALLFTCFLAVDTQLLLGNK-QLSLSPEEYVFAALNLYTDIINIFLYILTIIG 344

  Fly   321 ASRD 324
            .:::
  Rat   345 RAKE 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	103/216 (48%)
Grina	NP_695220.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..118		40/88 (45%)
		Pro-rich	<16..126	CDD:291893	44/101 (44%)
		Bindin	24..>105	CDD:251078	35/75 (47%)
		LFG_like	131..344	CDD:198410	103/213 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2719
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41517
Inparanoid	1	1.050	264	1.000	Inparanoid score	I2996
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm8911
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.780