DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmda1 and bxi1

DIOPT Version :9

Sequence 1:	NP_523722.1	Gene:	Nmda1 / 36419	FlyBaseID:	FBgn0013305	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_588431.1	Gene:	bxi1 / 2539556	PomBaseID:	SPCC576.04	Length:	266	Species:	Schizosaccharomyces pombe

Alignment Length:	276	Identity:	93/276 - (33%)
Similarity:	142/276 - (51%)	Gaps:	44/276 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PGGY--APQ-----PGFIQPPPSAGGYGAYDDPESQPKNFSFDD-----------QSIRRGFIRK 116
            |..|  .||     |...|.||:   |..|:  ||..:|.:.|.           :|||..|:||
pombe     2 PANYQSVPQDDPSVPNLAQAPPA---YSEYN--ESATENPAVDQFKNTTPVAECAKSIRMAFLRK 61

  Fly   117 VYLILMGQLIVT--FGAVALFVYHEGTKTFARNNMWL----FWVALGVMLVTMLSMACCESVRRQ 175
            ||.||..||.||  ||.:  |..|.....:.:.:.|.    |:::|.|:...::.       ...
pombe    62 VYAILTAQLFVTSLFGGI--FYLHPAFSFWVQMHPWFLILNFFISLVVLFGLIMK-------PYS 117

  Fly   176 TPTNFIFLGLFTAAQSFLMGVSATKYAPKEVLMAVGITAAVCLALTIFALQTKYDFTMMGGILIA 240
            .|.|:|||.||||.:...:|.:.|.::.:.:|.||.||..|.:|||.|..|:|:||:.:||.|..
pombe   118 YPRNYIFLFLFTALEGLTLGTAITFFSARIILEAVFITLGVFVALTAFTFQSKWDFSRLGGFLYV 182

  Fly   241 CMVVFLIFGIVAIFVKG-KIITLVYASIGALLFSVYLIYDTQLMMGGEHKYSISPEEYIFAALNL 304
            .:...::..::..||.. ..|.:.:|..|.|:|..|:::||..::   |:|  ||||:|.::|.|
pombe   183 SLWSLILTPLIFFFVPSTPFIDMAFAGFGTLVFCGYILFDTYNIL---HRY--SPEEFIMSSLML 242

  Fly   305 YLDIINIFMYILTIIG 320
            |||.||:|:.||.|:|
pombe   243 YLDFINLFIRILQILG 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	79/234 (34%)
bxi1	NP_588431.1	GAAP_like	29..261	CDD:198411	83/246 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1325
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1363
OMA	1	1.010	-	-		QHG57711
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		otm46971
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.800