DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmda1 and Y42H9AR.2

DIOPT Version :9

Sequence 1:	NP_523722.1	Gene:	Nmda1 / 36419	FlyBaseID:	FBgn0013305	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_501350.3	Gene:	Y42H9AR.2 / 189842	WormBaseID:	WBGene00021537	Length:	257	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	86/243 - (35%)
Similarity:	140/243 - (57%)	Gaps:	14/243 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GAYDDPESQPKN-----FSFDDQSIRRGFIRKVYLILMGQLIVTFGAVALFVYHEGTKTFA--RN 147
            |:.||.|..||:     |.|||:|||..|:.||:.::.....:|....|:.:|::..|.:.  .:
Worm    15 GSDDDNEEGPKDDIAVQFGFDDRSIRAAFVAKVFALVTVMFAITAAFSAVPIYNKDFKKWCNQED 79

  Fly   148 NMWLFWVALGVMLVTMLSMACCESVRRQTPTNFIFLGLFT-AAQSFLMGVSATKYAPKEVLMAVG 211
            :.|..:||:||..:..:::.||...||..|.|...|..|| :|.:..|.::|| |:...||:::.
Worm    80 HWWCVYVAMGVFFIFYITLMCCGRARRCFPCNLFILTCFTFSAATMTMFITAT-YSADAVLISLL 143

  Fly   212 ITAAVCLALTIFALQTKYDFTMMGGILIACMVVFLIFGIVA----IFVKGKIITLVYASIGALLF 272
            ||.....::.:||..||.|.|...|:.....:..::||::|    ||:..:.:.:|||.:||||.
Worm   144 ITTGCSASIILFAATTKKDLTSCLGVAFILGICLMLFGLMACIFCIFLNWQFLYIVYAVLGALLC 208

  Fly   273 SVYLIYDTQLMMGGEHKYSISPEEYIFAALNLYLDIINIFMYILTIIG 320
            ..||..|.||:||| .:..||||||||||.::::||:.:|:.||.::|
Worm   209 MFYLAIDIQLIMGG-RRVEISPEEYIFAATHVFVDILGMFLNILGVVG 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	78/223 (35%)
Y42H9AR.2	NP_501350.3	LFG_like	33..255	CDD:198410	78/223 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I2788
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm4835
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.760