DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lfg and BXI1

DIOPT Version :9

Sequence 1:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_014094.1	Gene:	BXI1 / 855411	SGDID:	S000005249	Length:	297	Species:	Saccharomyces cerevisiae

Alignment Length:	259	Identity:	73/259 - (28%)
Similarity:	122/259 - (47%)	Gaps:	52/259 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEWVQKNPALFWIALAVLIVTMICMA------ 87
            ||:.|:.|||.:|.||||.:..|....:.|.:.|.::..:.|||:|.:.|.:|:.|.:|
Yeast    46 IRQRFMHKVYSLLSCQLLASLSFCYWASVSTSLQNFIMSHIALFYICMVVSLVSCIWLAVSPRPE 110

  Fly    88 ----------------------------CCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEAD 124
                                        ...|.::|..|    |.:||::|::.|.:|...::.|
Yeast   111 DYEASVPEPLLTGSSEEPAQEQRRLPWYVLSSYKQKLTL----LSIFTLSEAYCLSLVTLAYDKD 171

  Fly   125 EVLMAVGITAAVALGLTLFALQTKYDFTMCGGVLVAC-----LVVFIIFGIIAIFI----PGKVI 180
            .||.|:.||..|.:|::|.||..:::..:.....:..     |.:.|..|:.|:..    .....
Yeast   172 TVLSALLITTIVVVGVSLTALSERFENVLNSATSIYYWLNWGLWIMIGMGLTALLFGWNTHSSKF 236

  Fly   181 GLVYASLGALLFSVYLVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGLSRN 244
            .|:|..|||:||:.||..||||:.     ..:.|:|.:..|:.|||||:|:|:.||.|:..|.:
Yeast   237 NLLYGWLGAILFTAYLFIDTQLIF-----RKVYPDEEVRCAMMLYLDIVNLFLSILRILANSND 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	72/253 (28%)
BXI1	NP_014094.1	GAAP_like	21..294	CDD:198411	72/256 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341661
Domainoid	1	1.000	91	1.000	Domainoid score	I1743
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I1487
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		oto100121
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
TreeFam	0	0.000	Not matched by this tool.
	11	10.730