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Protein Alignment Lfg and TMBIM1

DIOPT Version :9

Sequence 1:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001308356.1	Gene:	TMBIM1 / 64114	HGNCID:	23410	Length:	311	Species:	Homo sapiens

Alignment Length:	249	Identity:	102/249 - (40%)
Similarity:	158/249 - (63%)	Gaps:	15/249 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HYQQGDETGAYTDAEADKSFA---FDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEW 64
            |...|:|. |.:|     ||.   :||:.:|..||||||.|:..|||||...:::|||.:....:
Human    71 HGYDGEER-AVSD-----SFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAF 129

  Fly    65 VQKNPALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMA 129
            |::|.|:::::.||.:||.:.:|||:..||:.|.|.|.|.|||.|..|:.|.::..::...|::|
Human   130 VRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIA 194

  Fly   130 VGITAAVALGLTLFALQTKYDFTMCGGVL----VACLVVFIIFGIIAIFIPGKVIGLVYASLGAL 190
            :.|||.|::.:|:|..|||.|||.|.|:.    :..||..|:..|:..|.....:.::||:|||:
Human   195 MIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAI 259

  Fly   191 LFSVYLVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGLSRN 244
            .|:::|.|||||:| ||.|::||||:||..||.:|.|||.||.::|.::| .||
Human   260 CFTLFLAYDTQLVL-GNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMG-DRN 311

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.