Protein Alignment Lfg and TMBIM4

DIOPT Version :9

• Sequence 1: NP_725236.1
• Gene: Lfg / 36418
• FlyBaseID: FBgn0025692
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001269535.1
• Gene: TMBIM4 / 51643
• HGNCID: 24257
• Length: 285
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 82/226 - (36%)
• Similarity: 128/226 - (56%)
• Gaps: 24/226 - (10%)

  Fly    27 QSIRKG----------FIRKVYLILMCQLLITFGFVSVFTFSKASQEWVQKNPA---LFWIALAV 78
            ||.|.|          |:||||.||..|:|:|....:||.:.::.:.:|.::||   ||.:....
Human    65 QSGRSGMVNIFYKGPTFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLG 129

  Fly    79 LIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMAVGITAAVALGLTLF 143
            ||..:|..      |.|.|||...||.||:.|:..:.:|...::...:|.|..:|..|..|||::
Human   130 LIFALILN------RHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVY 188

  Fly   144 ALQTKYDFTMCGGVLVACLVVFIIFGIIAIFIPGKVIGLVYASLGALLFSVYLVYDTQLMLGGNH 208
            .||:|.||:..|..|.|.|.:..:.|.:..|...:::.||.|:.|||||..:::|||..::   |
Human   189 TLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLM---H 250

  Fly   209 KYSISPEEYIFAALNLYLDIINIFMYILTII 239
            |  :|||||:.||::|||||||:|:::|..:
Human   251 K--LSPEEYVLAAISLYLDIINLFLHLLRFL 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	82/226 (36%)
TMBIM4	NP_001269535.1	GAAP_like	6..283	CDD:198411	82/226 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2307
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.710