Protein Alignment Lfg and GRINA

DIOPT Version :10

• Sequence 1: NP_725236.1
• Gene: Lfg / 36418
• FlyBaseID: FBgn0025692
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_000828.1
• Gene: GRINA / 2907
• HGNCID: 4589
• Length: 371
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 115/241 - (47%)
• Similarity: 171/241 - (70%)
• Gaps: 2/241 - (0%)

  Fly     3 HYQQGDETGAYTDAEADKSFAFDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEWVQK 67
            :||: :...:|.|.:...:..:||:|||:.|||||:|:|..||.:|...||||||....:.:|::
Human   132 NYQE-EGPPSYYDNQDFPATNWDDKSIRQAFIRKVFLVLTLQLSVTLSTVSVFTFVAEVKGFVRE 195

  Fly    68 NPALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMAVGI 132
            |...::::.||..:::|.::||...|||.|.|.:.|.:.|.:.|:::||:|..:..:.|:|||||
Human   196 NVWTYYVSYAVFFISLIVLSCCGDFRRKHPWNLVALSVLTASLSYMVGMIASFYNTEAVIMAVGI 260

  Fly   133 TAAVALGLTLFALQTKYDFTMCGGVLVACLVVFIIFGIIAIFIPGKVIGLVYASLGALLFSVYLV 197
            |.||...:.:|::||:||||.|.|||:..:||..||.|:.|||..:::.:||||||||||:.:|.
Human   261 TTAVCFTVVIFSMQTRYDFTSCMGVLLVSMVVLFIFAILCIFIRNRILEIVYASLGALLFTCFLA 325

  Fly   198 YDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGLSR 243
            .||||:| ||.:.|:|||||:|||||||.||||||:|||||||.::
Human   326 VDTQLLL-GNKQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAK 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	109/216 (50%)
GRINA	NP_000828.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..145		4/13 (31%)
		Pro-rich	<43..139	CDD:464580	2/7 (29%)
		LFG_like	151..367	CDD:198410	109/216 (50%)