DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lfg and Faim2

DIOPT Version :9

Sequence 1:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_653357.1	Gene:	Faim2 / 246274	RGDID:	628744	Length:	316	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	107/244 - (43%)
Similarity:	159/244 - (65%)	Gaps:	8/244 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YQQGDETGAYTDAEADKSFAFDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEWVQKN 68
            |:.|...|.:   |...:|::|||.:|:.||||||.||:.|||:|...|::|||....:::||.|
  Rat    76 YEGGFPAGHH---ELFSTFSWDDQKVRQLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQAN 137

  Fly    69 PALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMAVGIT 133
            |..:|.:.||...|.:.:|||...||..|.|.|.|.:||::.::|.||::..:....||:.:|||
  Rat   138 PGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLGIT 202

  Fly   134 AAVALGLTLFALQTKYDFTMCGGVLVACLVVFIIFG-IIAIFIPGKVI---GLVYASLGALLFSV 194
            |.|.|.:|:|:.|||:|||.|.|||...|:.....| ::||.:|.:.:   ..|||.|||.:|::
  Rat   203 ALVCLSVTIFSFQTKFDFTSCHGVLFVLLMTLFFSGLLLAILLPFQYVPWLHAVYAVLGAGVFTL 267

  Fly   195 YLVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGLSR 243
            :|.:||||:: ||.::|:|||||||.|||:|||||.||.:.|.:.|.:|
  Rat   268 FLAFDTQLLM-GNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNR 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	100/220 (45%)
Faim2	NP_653357.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
Faim2	NP_653357.1	LFG_like	92..312	CDD:198410	100/220 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2719
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm8911
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930