DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lfg and Y42H9AR.2

DIOPT Version :9

Sequence 1:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_501350.3	Gene:	Y42H9AR.2 / 189842	WormBaseID:	WBGene00021537	Length:	257	Species:	Caenorhabditis elegans

Alignment Length:	240	Identity:	84/240 - (35%)
Similarity:	132/240 - (55%)	Gaps:	11/240 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DETGAYTDAEADKSFAFDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEWVQKNPALF 72
            :|.|...|...  .|.|||:|||..|:.||:.::.....||..|.:|..::|..::|..:... :
Worm    20 NEEGPKDDIAV--QFGFDDRSIRAAFVAKVFALVTVMFAITAAFSAVPIYNKDFKKWCNQEDH-W 81

  Fly    73 W---IALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMAVGITA 134
            |   :|:.|..:..|.:.||...||..|.|...|..||.:.:.:...:...:.||.||:::.||.
Worm    82 WCVYVAMGVFFIFYITLMCCGRARRCFPCNLFILTCFTFSAATMTMFITATYSADAVLISLLITT 146

  Fly   135 AVALGLTLFALQTKYDFTMCGGVLVACLVVFIIFGIIA----IFIPGKVIGLVYASLGALLFSVY 195
            ..:..:.|||..||.|.|.|.||.....:..::||::|    ||:..:.:.:|||.|||||...|
Worm   147 GCSASIILFAATTKKDLTSCLGVAFILGICLMLFGLMACIFCIFLNWQFLYIVYAVLGALLCMFY 211

  Fly   196 LVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIG 240
            |..|.||::|| .:..||||||||||.::::||:.:|:.||.::|
Worm   212 LAIDIQLIMGG-RRVEISPEEYIFAATHVFVDILGMFLNILGVVG 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	79/223 (35%)
Y42H9AR.2	NP_501350.3	LFG_like	33..255	CDD:198410	79/223 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I2788
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm4835
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.760