DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lfg and xbx-6

DIOPT Version :9

Sequence 1:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001379309.1	Gene:	xbx-6 / 179361	WormBaseID:	WBGene00009580	Length:	296	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	81/248 - (32%)
Similarity:	142/248 - (57%)	Gaps:	6/248 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYHYQQGDETGAYTDAEADKSFAFDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEWV 65
            |::..:..:.|...:.:...||.|.|:::|..|:|||:.::...|.|......:......:...|
Worm    51 MFNQMENGQHGGGDNPDGKYSFQFSDKTVRAAFVRKVFSLVFIMLCIVAAVTVIPWVHDDTMRMV 115

  Fly    66 QKNPALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMAV 130
            ::|.||:..:..:..||.:.:.|||.||||.|:|.|...:||:|.|.:..:::...:|:.||:|:
Worm   116 RRNSALYLGSYVIFFVTYLSLVCCEGVRRKFPVNLIVTGIFTLATSVMTMVISAHHDANVVLLAL 180

  Fly   131 GITAAVALGLTLFALQTKYDFTMCGGVLVACLVVFIIFGIIAI----FIPGKVIGLVYASLGALL 191
            .|.......:.:.|.|||:|.|...|.::...:.|:.||::.:    |...|.:.:|||..|||:
Worm   181 AICIGCTFSIVIVASQTKFDLTAHMGYILIISMCFMFFGLVVVICSMFFKIKFLMMVYALGGALI 245

  Fly   192 FSVYLVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGLSRN 244
            ..:||..|.|:::||. ||.|||||||||::.:::||:.:|.::|::.| |||
Worm   246 MMLYLFLDVQMLMGGK-KYEISPEEYIFASVQIFIDIVQMFWFLLSLFG-SRN 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	73/220 (33%)
xbx-6	NP_001379309.1	LFG_like	74..293	CDD:198410	73/219 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I2788
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I2681
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm4835
orthoMCL	1	0.900	-	-		OOG6_100360
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910