DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lfg and grina

DIOPT Version :9

Sequence 1:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001120085.1	Gene:	grina / 100145094	XenbaseID:	XB-GENE-5740104	Length:	286	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	117/244 - (47%)
Similarity:	158/244 - (64%)	Gaps:	11/244 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ETGAYT--DAEADK---------SFAFDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQ 62
            |..:|.  ||||..         |..|.:.:||:.|||||||.|..||.:|.|.:.:|.|.|..:
Frog    39 EANSYPEHDAEAGPPEYTFGVVGSSPFSESAIRRAFIRKVYLTLAMQLALTVGLICMFIFWKRLK 103

  Fly    63 EWVQKNPALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVL 127
            .|||:.|.:.:.....:|:..:.:|||:.||||.|.|||||.|||..|..:||.:|..|:||.|:
Frog   104 NWVQEYPYIVYALCPAIIILALVLACCQQVRRKVPYNFIFLGLFTAVEGCMLGTIAALFDADAVM 168

  Fly   128 MAVGITAAVALGLTLFALQTKYDFTMCGGVLVACLVVFIIFGIIAIFIPGKVIGLVYASLGALLF 192
            .|.|.|..|.||||:||||||:||||..|.|...|:|.:.|||:...:....:.:||||:|..:|
Frog   169 WAGGATIVVTLGLTIFALQTKWDFTMLSGGLCVALLVLLCFGILCGILRSMYLNIVYASIGTFIF 233

  Fly   193 SVYLVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGL 241
            .:|||.||||::||.|:|::|||||||||||:||||||:|:.:|.|.|:
Frog   234 GMYLVVDTQLIVGGKHRYAVSPEEYIFAALNIYLDIINLFLMLLQIFGI 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lfg	NP_725236.1	LFG_like	23..240	CDD:198410	109/216 (50%)
grina	NP_001120085.1	DUF4526	<4..>55	CDD:291688	6/15 (40%)
grina	NP_001120085.1	LFG_like	64..281	CDD:198410	109/216 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2553
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3354
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		otm47433
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.090