Protein Alignment Balat and SV2A

DIOPT Version :9

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001315603.1
• Gene: SV2A / 9900
• HGNCID: 20566
• Length: 742
• Species: Homo sapiens
• Alignment Length: 635
• Identity: 119/635 - (18%)
• Similarity: 194/635 - (30%)
• Gaps: 249/635 - (39%)

  Fly   105 LRQQAEDLLKLQPDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGV------ 163
            |.||.|.:|:         .|.||..            :|.|.    |::.|||:..||
Human   148 LAQQYEAILR---------ECGHGRF------------QWTLY----FVLGLALMADGVEVFVVG 187

  Fly   164 --------------------------GGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFA 202
                                      |.::|.:::|.|.|..|||......|.:..:....|:|.
Human   188 FVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252

  Fly   203 WNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERR--------VFCTIVSNIAYSLGLVVL-- 257
            ..|.|:|..|.:.|:.:...:...:....|.:..|:|        :|..|....|.::...::
Human   253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPH 317

  Fly   258 ------AGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNG 316
                  .|..|....||...|..:.|.:.........|||||:.:..||...|..:||.:...|
Human   318 YGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTN- 381

  Fly   317 VRVNRDFVERL-----------QRKLVITRAAETKSSMTTHY----------------GILDLFR 354
            :|. :...||:           :.:|:     |.:|...|.|                ..|..|
Human   382 MRA-KGHPERVFSVTHIKTIHQEDELI-----EIQSDTGTWYQRWGVRALSLGGQVWGNFLSCF- 439

  Fly   355 GPNMRRKTLIITLIWFANTSVYVGLSYYAP----------------ALGGDEI----WNFFLAGA 399
            ||..||.||::..:||..:..|.||:.:.|                ...|:.:    :||.|...
Human   440 GPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYASRTKVFPGERVEHVTFNFTLENQ 504

  Fly   400 VELPTYLLLWPGLSYFGRRWI-------------------------------------------L 421
            :.        .|..||..::|                                           |
Human   505 IH--------RGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDL 561

  Fly   422 FISMLVGGVACVATFLYP------DIT----------------------------LLLYCVGKM- 451
            |....|......:|||:.      |:|                            ||:..:|::
Human   562 FEYKFVNSRLINSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLR 626

  Fly   452 ---------------------------------GIS-SSFVVLPLMASELYPTVVRGLGMSFSSV 482
                                             |:| :|:..|.::..||||:..|.....|.:.
Human   627 MLAGSSVMSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNA 691

  Fly   483 ISMVGPIV-IPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNL 531
            :..:..:: |.:...........|::...|.|.||...:|.|||||.:.|
Human   692 LCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVL 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	106/603 (18%)
SV2A	NP_001315603.1	synapt_SV2	1..742	CDD:130366	119/635 (19%)
		Interaction with SYT1. /evidence=ECO:0000250	1..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..144

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940