DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Balat and OCT2

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_178054.1	Gene:	OCT2 / 844274	AraportID:	AT1G79360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	127/458 - (27%)
Similarity:	197/458 - (43%)	Gaps:	43/458 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 WHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVD-LWGRRPSFYAYLLLE 192
            |.:|.|.:.| |:.||.|.|..||:..|....|.||.|:|..|...|.| ..||:...:...|:.
plant    89 WSWDYSPHVS-VISEWGLQCAGSFVKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSCLVM 152

  Fly   193 IIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLVVL 257
            .|:...:.|:.|.:.:..||||.|.....|.....||:.||||.:.|....|:|...:.||.:.|
plant   153 AISTMLTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTELVGKKWRGRVGIMSFFGFMLGFLSL 217

  Fly   258 AGVIYIVR--DWRELSLAVSMPLLMLFSC----FFVLPESPRWLMAVGKTRRAIKILKVMARVNG 316
            ..:.|:.|  .||.|....|:|.::.  |    |||. ||||||...|:...||.|||.:|.:..
plant   218 PLMAYMNRGSSWRILYAWTSIPTIIY--CVLVRFFVC-ESPRWLFVRGRREEAISILKRVASIPS 279

  Fly   317 VRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTL----IITLIWFANTSVYV 377
            ..|:......:....:.....|.|.|  |:..|....:....:|..|    .:..|.|.     :
plant   280 TDVSSGGAISMSFSSLPFEEDEEKPS--TNVNIFTTMKVLVEKRWALKRLSAVMAIAFG-----I 337

  Fly   378 GLSYYAPALGGDEI-WNFFLAGA----VELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFL 437
            ||.||...|....: :|.:|:.|    ::||..|:....:....||..|.....:|||:.|..|.
plant   338 GLVYYGMPLALSNLDFNIYLSAAFNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSVLIFA 402

  Fly   438 --------YPDITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMI 494
                    :..:.|.|..:......|:|.:..:...||:||.||...::.:....::|.:..|::
plant   403 LHNMRIGNHGALQLALELISYFSACSAFNMEMIYTIELFPTCVRNSAIAMARQALVLGGVFSPIM 467

  Fly   495 NHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNN 559
            ...|::.......:.|..:.|.|..::.|||||..:|..|::|.|        |....|:...||
plant   468 VAAGRKNAFWSFGLFGLAIGLLGLFAVGLPETRGSDLCDTMDEEE--------CKDRRSKVAVNN 524

  Fly   560 IRA 562
            :.|
plant   525 VIA 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	113/418 (27%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	113/418 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm8406
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.020