Protein Alignment Balat and Sv2a

DIOPT Version :9

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_071313.1
• Gene: Sv2a / 64051
• MGIID: 1927139
• Length: 742
• Species: Mus musculus
• Alignment Length: 634
• Identity: 119/634 - (18%)
• Similarity: 195/634 - (30%)
• Gaps: 247/634 - (38%)

  Fly   105 LRQQAEDLLKLQPDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGV------ 163
            |.||.|.:|:         .|.||..            :|.|.    |::.|||:..||
Mouse   148 LAQQYETILR---------ECGHGRF------------QWTLY----FVLGLALMADGVEVFVVG 187

  Fly   164 --------------------------GGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFA 202
                                      |.::|.:::|.|.|..|||......|.:..:....|:|.
Mouse   188 FVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252

  Fly   203 WNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERR--------VFCTIVSNIAYSLGLVVL-- 257
            ..|.|:|..|.:.|:.:...:...:....|.:..|:|        :|..|....|.::...::
Mouse   253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPH 317

  Fly   258 ------AGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNG 316
                  .|..|....||...|..:.|.:.........|||||:.:..||...|..:||.:...|
Mouse   318 YGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTN- 381

  Fly   317 VRVNRDFVERL-----------QRKLVITRAAETKSSMTTHY---GILDLFRG------------ 355
            :|. :...||:           :.:|:     |.:|...|.|   |:..|..|
Mouse   382 MRA-KGHPERVFSVTHIKTIHQEDELI-----EIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFS 440

  Fly   356 PNMRRKTLIITLIWFANTSVYVGLSYYAP----------------ALGGDEI----WNFFLAGAV 400
            |..||.||::..:||..:..|.||:.:.|                ...|:.:    :||.|...:
Mouse   441 PEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFNFTLENQI 505

  Fly   401 ELPTYLLLWPGLSYFGRRWI-------------------------------------------LF 422
            .        .|..||..::|                                           ||
Mouse   506 H--------RGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLF 562

  Fly   423 ISMLVGGVACVATFLYP------DIT----------------------------LLLYCVGKM-- 451
            ....|......:|||:.      |:|                            ||:..:|::
Mouse   563 EYKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRM 627

  Fly   452 --------------------------------GIS-SSFVVLPLMASELYPTVVRGLGMSFSSVI 483
                                            |:| :|:..|.::..||||:..|.....|.:.:
Mouse   628 LAGSSVLSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNAL 692

  Fly   484 SMVGPIV-IPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNL 531
            ..:..:: |.:...........|::...|.|.||...:|.|||||.:.|
Mouse   693 CKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVL 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	106/602 (18%)
Sv2a	NP_071313.1	synapt_SV2	1..742	CDD:130366	119/634 (19%)
		Interaction with SYT1. /evidence=ECO:0000250	1..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..145

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940