Protein Alignment Balat and sv2a

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 667
• Identity: 126/667 - (18%)
• Similarity: 212/667 - (31%)
• Gaps: 242/667 - (36%)

  Fly    71 IPRNRN--------GAYAECSMYSRNYTDIVRYL-EYRPPPDLLRQQAEDLLKLQPDTTQVVPCQ 126
            ||||.:        ||..:     ..:.|:.:|. |.|...:.|.||.|.:|:         .|.
Zfish   102 IPRNDSVEKADRQVGAVGQ-----SQFRDMTQYEGERRKDQEELAQQYETILQ---------ECG 152

  Fly   127 HGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGV---------------------------- 163
            ||..            :|.|.    |::.|||:..||
Zfish   153 HGRF------------QWTLY----FVLGLALMADGVEIFVVGFVLPSAEKDMCLSEPNKGMLGL 201

  Fly   164 ----GGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILA 224
                |.::|.:|:|.|.|..|||.:....|.:..:....|:|...|.::|..|.:.|:.:...:.
Zfish   202 IVYLGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIP 266

  Fly   225 SPYVLAIELVGPERR--------VFCTIVSNIAYSLGLVVL--------AGVIYIVRDWRELSLA 273
            ..:....|.:..|:|        :|..|....|.::...::        .|..|....||...|.
Zfish   267 IVFSYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLV 331

  Fly   274 VSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFVERL----------- 327
            .:.|.:...:....:|||||:.:..||...|..|||.:...| :|. :.:.||:
Zfish   332 CAFPSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTN-MRA-KGYPERVFSVTTIKTVKQ 394

  Fly   328 QRKLVITRAAETKSSMTTHYGILDLFR----------GPNMRRKTLIITLIWFANTSVYVGLSYY 382
            ..:||......|.........:.:||.          .|..||.|.::..:||:.:..|.||:.:
Zfish   395 MDELVDMGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYGLTVW 459

  Fly   383 APAL------------------------------------GGDEIWNFFL--------------- 396
            .|.:                                    .|:...|.||
Zfish   460 FPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFE 524

  Fly   397 ------------------------------------------------AGAV-----ELPTYLLL 408
                                                            .|.:     |...|::.
Zfish   525 ECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNAYMIY 589

  Fly   409 WPGLSYFGRRWIL--------------FISMLVGG--VACVATFLY-----PDITLLLYCV-GKM 451
            :  :|:.|...:|              .:.||.|.  ::||:.|..     ....:.|.|: |
Zfish   590 F--VSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVISCVSCFFLSFGNSESAMIALLCLFG-- 650

  Fly   452 GIS-SSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIV-IPMINHMGQQMLVLPLIVMGALLI 514
            ||| :|:..|.::..||||:..|.....|.:.:..:..:: |.:..........:|::.....|.
Zfish   651 GISIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSFVGITKAVPILFASGALA 715

  Fly   515 LGGFASLLLPETRNRNL 531
            .|.|.:|.|||||.:.|
Zfish   716 AGSFLALKLPETRGQVL 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	103/592 (17%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	126/667 (19%)