Protein Alignment Balat and slc22a23

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001338637.1
• Gene: slc22a23 / 555979
• ZFINID: ZDB-GENE-030131-3564
• Length: 942
• Species: Danio rerio
• Alignment Length: 654
• Identity: 155/654 - (23%)
• Similarity: 257/654 - (39%)
• Gaps: 177/654 - (27%)

  Fly     6 VLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQLVKNLS 70
            ||..||.||.|||.:|....:||.. ..|..:|..|:...|   |  ||
Zfish    41 VLPSVGGFGKYQKQLIVLTWIPAIF-IGFSQFSDNFLLTNP---C--PE---------------- 83

  Fly    71 IPRNRNG--------------------AYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKL 115
             |.|.:.                    |.::|:....:|                        ||
Zfish    84 -PHNNSSQLLTVAPTAVSTVFTGVNTEAASQCNCTPSSY------------------------KL 123

  Fly   116 QPDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWG 180
            |....|                 .:|.:||||||.::.:.:|.....||.:.|..|.|.|.|.:|
Zfish   124 QNGLEQ-----------------NIVTKWNLVCDSAWKIHIAKFSLLVGSIFGYLVLGVLADWFG 171

  Fly   181 RRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIV 245
            |.|.....::..::.....||:.|...:..|||..|..:..|..|.|||.|||..|..|...|:|
Zfish   172 RHPVLILSVVFLLVFGMTVAFSVNLPMFGTLRFFEGFCLAGITLSLYVLRIELCLPGWRFSITMV 236

  Fly   246 SNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKV 310
            :|.....|.:::.|:..:.|||:.|...:..|||::.|..:..|||.|||:|..:..|:..|::.
Zfish   237 ANFMMLAGQLLMPGLAALCRDWQILQAVIVCPLLLMLSYIWAFPESLRWLLATQQYSRSKWIMER 301

  Fly   311 MARVNGVRVNRD----------FVERLQRKLVITRAAETKS----------SMTTHYGILDLFRG 355
            :::.|.:.:..|          .:::..:|..|.:...|::          :..|.|||...|..
Zfish   302 ISKKNNINLQEDAEELMTELNGALQKQPKKTCIVKMVGTRNLWKNIVVLCVNSLTGYGIHHCFAR 366

  Fly   356 PNMRRKTLIITLIWFANTSVYVGL-----SYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYF 415
            ..|.:||              ||.     .:||         .:::...:.:.:.:.|.|.::..
Zfish   367 SMMEKKT--------------VGFVEKLHDFYA---------EYYVMAVIAVASCVFLCPAVALM 408

  Fly   416 GRRWILFISMLVGGVACVATFLYPDITL-LLYCVGKMG--------------ISSSFVVLPLMAS 465
            |||..|.:.|::..:|.:       :.| ||..:||.|              .|.:|.::.:.:|
Zfish   409 GRRGGLLMFMIITALASL-------LQLGLLNLLGKYGDHLSLVHSDELNDKFSVAFSIIGMFSS 466

  Fly   466 ------------ELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGF 518
                        |:.|:|:||.|:......:..|.:..|::....|:...|..|:.....::...
Zfish   467 HAVSNLSIFFCAEITPSVIRGGGLGLVLASAGFGMLTSPIMELHNQKGYFLHHIIFACCTLICII 531

  Fly   519 ASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNNIRASPKKRILPEAGTPVFHRV-DT 582
            ..||||||||:.||:||.:||:.....||     ..|||..     ::.:|.::.:..:.|| ||
Zfish   532 CILLLPETRNQPLPETLSDGESYTRQPLL-----PPRKPGE-----QRLLLTKSESREYARVGDT 586

  Fly   583 PVSD 586
            |:.:
Zfish   587 PLHE 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	104/447 (23%)
slc22a23	NP_001338637.1	MFS_SLC22A23	108..523	CDD:341002	109/485 (22%)
		DUF5585	<565..921	CDD:465521	7/31 (23%)