DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and oatx

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	594	Identity:	167/594 - (28%)
Similarity:	283/594 - (47%)	Gaps:	37/594 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQL 65
            |.|.::|.|||.||.:|.:.:..:.:|..|..:.:..:. |.|..|:|.||:|.:.....|....
Zfish     1 MGFADLLDEVGGFGRFQMIHVTLLSIPGLLMASQNLLNN-FTAGVPEHHCRIPNVTTAMNDSTTT 64

  Fly    66 VKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHGWH 130
            :....||.:.:...::||.|......::       ...|....|.:|        |...|..||.
Zfish    65 LLRAFIPLDSSLTLSKCSRYKDTQWHLI-------TDKLSHGNATEL--------QTEGCADGWT 114

  Fly   131 YDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRP-SFYAYLLLEII 194
            ||||.:.|::|.||:|||....|..::..::..|.|.|..:||.|.|.:||:. ..::|..|.::
Zfish   115 YDKSEFISSIVSEWDLVCTLRPLKQMSQTIYMGGVLTGAIIFGGLSDRFGRKALLIWSYFQLALL 179

  Fly   195 ACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLVVLAG 259
            . :.:|.|.:|..:...||:.|::|..::.:...|.:|.:..:.|.....:|:..::.|.:||||
Zfish   180 G-SFTALAPSYVVYCIFRFLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAG 243

  Fly   260 VIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFV 324
            |.|.:||||::.:||.:|..:.|...:...||.|||:..|::..|:|:|..:|::||   ..:..
Zfish   244 VAYSLRDWRKIQMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKING---KPEMT 305

  Fly   325 ERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAPALGGD 389
            |::..:.:.:...:...|..:.|.:.||.|.|.||:.::.:.::||:.:..|.||:......|.:
Zfish   306 EKITLEELESHMQKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVN 370

  Fly   390 EIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYPD---IT-LLLYCVGK 450
            ......:.|||:.|..|:....||:.|||......:||......|....|:   :| ..|..:||
Zfish   371 IYLMQVIFGAVDFPAKLVALLMLSFLGRRLTQGACLLVSASIIFANIFVPEDMQVTRTALAVLGK 435

  Fly   451 MGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGALLIL 515
            ...|:||..:.|...||||||:|..||.|.|.:|.:|.:..|.:..:...:..||.||.|...::
Zfish   436 GFTSASFTCVYLFTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIVYGGSAVI 500

  Fly   516 GGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNNIRASPKKRILPEAGTPVFHRV 580
            .|..:.|||||.|..||.|:::.|            |...|.||.......:.:.:.|.......
Zfish   501 AGLIAFLLPETLNIPLPDTIDDVE------------EKWEKKNNTAEDLALQDVKQVGGAHEENN 553

  Fly   581 DTPVSDRVP 589
            .||.::..|
Zfish   554 STPAAEANP 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	121/400 (30%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.050