Protein Alignment Balat and SLC22A15

DIOPT Version :9

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 159/564 - (28%)
• Similarity: 258/564 - (45%)
• Gaps: 96/564 - (17%)

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIA---ATPQHFCRVPELEPWTQDY 62
            |:.:|..:.||..|:|| :.:|.:|  |.|...:.|...:.||   |||.:.        |  |.
Human     1 MEVEEAFQAVGEMGIYQ-MYLCFLL--AVLLQLYVATEAILIALVGATPSYH--------W--DL 52

  Fly    63 VQLVKNLSIPRNRNG---AYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVP 124
            .:|:.|.|......|   |:.:. :.:.|.::|.:::
Human    53 AELLPNQSHGNQSAGEDQAFGDW-LLTANGSEIHKHV---------------------------- 88

  Fly   125 CQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYL 189
                 |:..|.  :::..||.|:.:||:.|:.|...|..|..:|...||.|.|.:||:..:....
Human    89 -----HFSSSF--TSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146

  Fly   190 LLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGL 254
            .|:|:...|:.|:.:|..:...||:||:....:....:||..|.||.........:..:.:::|:
Human   147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGI 211

  Fly   255 VVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRV 319
            ...|.:.|.:|.||.|::.|::...::|.....:|||||||.:.|:...|.:.|.::|:.|
Human   212 AQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN---- 272

  Fly   320 NRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAP 384
                 .:|:....:|..|......|..:  |||||...:...|||:..|||..:.||.||:..|.
Human   273 -----RKLKCTFSLTHPANRSCRETGSF--LDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAG 330

  Fly   385 ALGGDEIWNFFLAGAVELPTYLLL-------WPGLSYFGRRWILFISMLVGGVACVATFLYPD-- 440
            .|||....|..|:|.:|:|:|.|.       |     |||:..|...:.:||:||:.....|:
Human   331 DLGGSIYANLALSGLIEIPSYPLCIYLINQKW-----FGRKRTLSAFLCLGGLACLIVMFLPEKK 390

  Fly   441 ------------ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPM 493
                        ::||    ||:.||::|.::.:..|||||||:|.:|:...|:.|.||.|:.|.
Human   391 DTGVFAVVNSHSLSLL----GKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPF 451

  Fly   494 INHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEE 537
            |..:......||.||.||..:..|..|||||||.|..|.:|..:
Human   452 IPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSD 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	126/416 (30%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	113/377 (30%)
		MFS_1	111..450	CDD:284993	107/358 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850