Protein Alignment Balat and SLC22A17

DIOPT Version :9

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 152/630 - (24%)
• Similarity: 253/630 - (40%)
• Gaps: 117/630 - (18%)

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRV----PELEPWTQD 61
            :.|:.:|.:||:.|..|::.:....||........|...:|..|.|.| |..    |....|.|
Human    78 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLH-CHYGAFPPNASGWEQ- 140

  Fly    62 YVQLVKNLSIPRNRNG-----AYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQ 121
                      |.|.:|     |....|..||..|..........|||...
Human   141 ----------PPNASGVSVASAALAASAASRVATSTDPSCSGFAPPDFNH--------------- 180

  Fly   122 VVPCQHGWHYD-KSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSF 185
               |...|.|: ..:.::..:.:|:||||..:.|.|..::|.:|...|....||..|.:|||.
Human   181 ---CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG-- 240

  Fly   186 YAYLLLEIIA-CAASAFAWNYYTW-LGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNI 248
            ...|.|.::. |.....|....|. :.|||::|..:..:....|::.:||..|.:|:...:...:
Human   241 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGEL 305

  Fly   249 AYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLP----ESPRWLMAVGKTRRAIKILK 309
            ....|..:..|:..:.:|||.|...::.|.::..  |:..|    ||.|||:...:...|..:|:
Human   306 VGVGGHFLFLGLALVSKDWRFLQRMITAPCILFL--FYGWPGLFLESARWLIVKRQIEEAQSVLR 368

  Fly   310 VMA---RVNGVRVNRDFVERLQRKLVITRAAETKSS----MTTHYGILDLFRGPNMRRKTLIITL 367
            ::|   |.:|..:..:..|.||         :.:::    .|:.:....|....|:.:..||
Human   369 ILAERNRPHGQMLGEEAQEALQ---------DLENTCPLPATSSFSFASLLNYRNIWKNLLI--- 421

  Fly   368 IWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLL----LWPGLSYFGRRWILFISMLVG 428
            :.|.|...:.....|.|..||....:|:|...:...|..|    |...:..||||.||.:||.:.
Human   422 LGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLT 486

  Fly   429 GVACVATF--------LYPDI--------------TLLLYCVGKMGISSS---FVVLPLMASELY 468
            |:|.:...        ::|.:              .:..:.|  :|:.||   .::..|:|:|:.
Human   487 GIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSV--LGLFSSQAAAILSTLLAAEVI 549

  Fly   469 PTVVRGLGMSFSSVISMVGPIVIPMIN-HMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLP 532
            ||.|||.|:.....:..:|.:..|... |||.... |..:|:.|..:|...:.:|||||:.:.||
Human   550 PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAF-LQHVVLAACALLCILSIMLLPETKRKLLP 613

  Fly   533 QTLEEGEAVPLSFLLCCCVESERKPNNIRASPKKRI--LPEAGTP 575
            :.|.:||       ||      |:|:.:|..|..|.  :|...||
Human   614 EVLRDGE-------LC------RRPSLLRQPPPTRCDHVPLLATP 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	104/439 (24%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940