DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and CG17752

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_650817.1	Gene:	CG17752 / 42337	FlyBaseID:	FBgn0038718	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	593	Identity:	164/593 - (27%)
Similarity:	267/593 - (45%)	Gaps:	104/593 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQL 65
            ||...||.:.|:||.|| :::..:.....:..:.|.:||..|:.||.|.|..| :|.::|::.:|
  Fly     1 MDLQRVLEKCGNFGPYQ-ILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAP-VEEFSQNFTEL 63

  Fly    66 VKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHGWH 130
            :              .||        :::|       |:      |:...:.:     .|. .|.
  Fly    64 L--------------SCS--------VIQY-------DV------DMTSFRDN-----KCS-SWD 87

  Fly   131 YDK-SIYSS-TVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEI 193
            :|| |.|.| |...||  |||.::.:.:....|.:|..||:..||||.|..||.|:    .:|..
  Fly    88 FDKESNYESITTELEW--VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPA----CVLST 146

  Fly   194 IACAASAFAWNYYTWLGL----RFVVGLTVPAILASPYVLAIELVGPERRVF-CTIVSNIAYSLG 253
            :..|:..|..::...|.:    ||:.||::.......|:|..|.:.|:.|.| ..|:..:.||:|
  Fly   147 LTGASGDFFTSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIG 211

  Fly   254 LVVLAGVIYIVRDWRELSLAVSMPLL--MLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNG 316
            |::...:...:.:||....|.|:|.|  ::|..|  |.||..||:..||..:|:..||.:|:.||
  Fly   212 LMISPWIAIWLGNWRSYLWAASLPALGMLIFPLF--LHESVEWLLTKGKFDKAVNNLKSVAKFNG 274

  Fly   317 VRVN----RDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYV 377
            .:|.    .:|::..:.||   .:|:.|||.|    .:.:.|.|.:|:.|:|:.:.....|..:.
  Fly   275 RQVEDSVFDEFIKHYREKL---NSAQKKSSDT----FMGMLRTPRLRKFTIILLIKSMIITIAFD 332

  Fly   378 GLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVAT-FL---- 437
            .||.....:|......|..:|.|.||..|.:....:..||:.:...|:|||......| :|
  Fly   333 ILSRNVEGVGISPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTL 397

  Fly   438 ----YPDITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMS-----------FSSVISMVG 487
                |..:...:.|:.:.|...::......|:|:.||.|||.|::           |||.|..:|
  Fly   398 DPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLG 462

  Fly   488 PIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGE--AVPLSFLLCCC 550
            ....|           ||.:::..|||:|....|.||||.::.|||||||||  |....:....|
  Fly   463 TFYKP-----------LPSLLISFLLIIGACLCLTLPETLHKQLPQTLEEGEIFAKGEKWYFFPC 516

  Fly   551 VESERKPN 558
            ...:|:.|
  Fly   517 FSRKRQSN 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	120/428 (28%)
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	149/555 (27%)
CG17752	NP_650817.1	MFS	116..488	CDD:119392	108/395 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458533
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	1	0.950	-	0	Normalized mean entropy	S5187
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	6.940