DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and CG7342

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	572	Identity:	152/572 - (26%)
Similarity:	249/572 - (43%)	Gaps:	108/572 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDEVLREVGSFGLYQKVII---CSVLLPAALPCAFHAYSQLFIAATPQHFCR--VP-ELE-PW 58
            ::.|::|.:.|.|...|.:::   |.:.:.:||    |.|||..|:..|:::|.  :| .:| |.
  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSAL----HYYSQTIISFVPKYWCADGLPASIESPV 62

  Fly    59 TQDYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVV 123
            ....:.|.:|:|.|.         :.||.||.   .|:.|                      |..
  Fly    63 DSSCLPLNRNISTPN---------TCYSYNYE---LYMGY----------------------QSF 93

  Fly   124 PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAY 188
            |.:..|                 ||..::.:||...:|.||.::|:.|.|||.|:.||.|.....
  Fly    94 PSEMDW-----------------VCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVA 141

  Fly   189 LLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPE-RRVFCTIVSNIAYSL 252
            .|:.:.....:.::.|...:...|.:.|:...:.....|:|.:|.:.|. |.:..:|.....|.|
  Fly   142 NLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCL 206

  Fly   253 GLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGV 317
            |.:....:..::|.||...|..|:|||::...:.::|||.:||::..|...|:..||.:|::||.
  Fly   207 GSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGR 271

  Fly   318 RVNR----DFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVG 378
            .|..    :|:|.       .:.::.....:.|  :||||:.|.:||.|||:.......|..|..
  Fly   272 HVEESAYAEFIEE-------CKCSQQNQKASPH--LLDLFQTPRLRRHTLILFFKSMVITLCYDA 327

  Fly   379 LSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLV--------GGVACVAT 435
            :|.....||......|.|:....||..||:.......||:.:...|:|:        ||:...|:
  Fly   328 VSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAAS 392

  Fly   436 FLYPDITLL--LYCVGKMGISSSFVVLPLMASELYPTVVRGLGMS-----------FSSVISMVG 487
            ......|||  |..||:.|::.::......|:||.||.|||.|::           ||:.|....
  Fly   393 ASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTR 457

  Fly   488 PIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGE 539
            .:..|           ||.|::|.|.:||....||||||.:|.||.:||:||
  Fly   458 SVFSP-----------LPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGE 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	111/421 (26%)
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	144/553 (26%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	39/166 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458530
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990