DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and CG8925

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_650526.1	Gene:	CG8925 / 41963	FlyBaseID:	FBgn0038404	Length:	670	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	140/533 - (26%)
Similarity:	245/533 - (45%)	Gaps:	58/533 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CSVLLPAALPCAFHAYSQLFIAATPQHFCRVPE------LEPWTQDYVQLVKNLSIPRNRNGAYA 80
            |::|......|.||.:..:|..|....:|..||      :..|        :|:|  ::.||
  Fly   165 CALLSIFQAICTFHIFVYVFQIAPKDFWCARPENLMQMSVSEW--------RNIS--QSSNG--- 216

  Fly    81 ECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHGWHYDKSIY---SSTVVQ 142
             |.:...:||.:.             .:...|:. .|:....:..:..||::.|..   :.|:||
  Fly   217 -CLLLDVDYTQVT-------------YENNQLIN-WPENATDLGYRQCWHFEFSDVDGSAKTLVQ 266

  Fly   143 EWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFAWNYYT 207
            |::|||.|..| :|....|.||...|..:.|::.|.:|||.:..|::.::.:.....||:.:...
  Fly   267 EFDLVCGRDIL-SLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTSVAM 330

  Fly   208 WLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSL 272
            ::.||.::|.....:....:||.:|||..:.|....|::.:..::..|:.||:.|::||||.|.|
  Fly   331 FMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGLAYLIRDWRHLQL 395

  Fly   273 AVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFVERLQRKLVITRAA 337
            |:|.|.|::.|.:|.||||||||:|.|:......:::..||:||...:.....|...:..:.||.
  Fly   396 AISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSNYRKTLEAAVPRAV 460

  Fly   338 ETKSSMTT------------------HYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAP 384
            ::....||                  |...|.:.......|.|.:..:||.....:|.||:.:..
  Fly   461 QSPPEATTSVESKAVEADAPDPSASGHVNPLLVVFSAKYWRTTCLTLVIWLTLIIIYFGLTLHLS 525

  Fly   385 ALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYPDIT--LLLYC 447
            .|||:...|..:||.||..:..:....:...|.|..|...||:.|:.|:||.|..:.|  :.|..
  Fly   526 NLGGNIYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLLPGLCCLATNLVSNQTGVIALAT 590

  Fly   448 VGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGAL 512
            :.|..|.::..::|...:..|||:||..|:...::.|.:..|::|.:..:.....:|||.|||..
  Fly   591 IAKCLIGANNAIIPTYTAMQYPTIVRNFGVGMGNLASGIALILVPFLWKLEHIDPLLPLNVMGVC 655

  Fly   513 LILGGFASLLLPE 525
            .::|..|..|:.:
  Fly   656 GLIGAVAISLMKD 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	120/418 (29%)
CG8925	NP_650526.1	MFS	277..667	CDD:119392	109/390 (28%)
CG8925	NP_650526.1	MFS_1	277..635	CDD:284993	99/358 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	6.060