DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Balat and CG14856

DIOPT Version :9

Sequence 1:NP_610823.1 Gene:Balat / 36417 FlyBaseID:FBgn0033778 Length:604 Species:Drosophila melanogaster
Sequence 2:NP_650391.1 Gene:CG14856 / 41790 FlyBaseID:FBgn0038261 Length:557 Species:Drosophila melanogaster


Alignment Length:561 Identity:145/561 - (25%)
Similarity:231/561 - (41%) Gaps:66/561 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQL 65
            |||||:|.:.|....||.:::....|...: .:.|.::|..|...|.|:|...:||         
  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFI-VSRHYFAQNVIGFVPDHWCYHEQLE--------- 57

  Fly    66 VKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPD----TTQVVPCQ 126
                      |.:|||.:..            |.|   ..|.....|..:..|    |....||.
  Fly    58 ----------NRSYAEIAAI------------YAP---FKRPSCTRLASINMDGSNATASSEPCN 97

  Fly   127 HGW--HYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYL 189
            . |  |||....|......|  |||.::...:...:|.||.:.|..:||.|.|..||..:.....
  Fly    98 R-WIYHYDHGFISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLAN 159

  Fly   190 LLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPE-RRVFCTIVSNIAYSLG 253
            ....:..:|:.||....|:...|||.||...|.....::|.:|.|.|. |.|...:...:.|.||
  Fly   160 CCGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLG 224

  Fly   254 LVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVR 318
            ::..:.....:..||...:..::|.|::...:|::.||.:||:.......|...|:.:|:.|   
  Fly   225 MICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFN--- 286

  Fly   319 VNRDFVE---RLQRKLVITRAAETKS--SMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVG 378
             .||..|   .|.|:...|:.:|.:|  ||.....::|.|:.|.:|.:.:.:|:::...|..|..
  Fly   287 -RRDVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNT 350

  Fly   379 LSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLY----- 438
            :|.....|.......|.|......|:.:.......:|||::...:||...|:....|.:.     
  Fly   351 MSRNVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWT 415

  Fly   439 -----PDITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMG 498
                 ..:.|||.|  :.|||.:......:::||.||.||..|::...|.:.....:.|.|.|:.
  Fly   416 QHSATVMVCLLLMC--RFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLD 478

  Fly   499 QQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGE 539
            ........|:...||::..:..|||.||||:.||.||.|||
  Fly   479 TYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGE 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BalatNP_610823.1 MFS_SLC22 128..524 CDD:340875 103/413 (25%)
CG14856NP_650391.1 2A0119 13..514 CDD:273328 134/544 (25%)
MFS 129..503 CDD:119392 93/379 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45458527
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24064
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X24
43.940

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