DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and CG14855

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_650390.2	Gene:	CG14855 / 41789	FlyBaseID:	FBgn0038260	Length:	556	Species:	Drosophila melanogaster

Alignment Length:	566	Identity:	151/566 - (26%)
Similarity:	237/566 - (41%)	Gaps:	79/566 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDEVLREVGSFGLYQKVIIC--SVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYV 63
            |||:|:|.:.|:...||.|::.  ..|:   :..:.|.:||..|:..|.|:|...:||
  Fly     1 MDFEEILAKCGNSSRYQFVLLALYGYLM---VVVSMHYFSQNVISFVPDHWCYHEQLE------- 55

  Fly    64 QLVKNLSIPRNRNGAYAECSMYSRNYTDIVR-YLEYRPPPDLLRQQAEDLLKLQPD----TTQVV 123
                                  :|::.:|.: |.::..|      ....|.|:..|    |....
  Fly    56 ----------------------NRSFAEIEKIYSQFEKP------SCTRLEKIDEDGQNHTLSRE 92

  Fly   124 PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAY 188
            .|.. |.|.......::..|.|.|||.::...:...:|.||.:.|...||.|.|..||..:....
  Fly    93 RCNR-WIYKYDFGYKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILA 156

  Fly   189 LLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPE-RRVFCTIVSNIAYSL 252
            .....:...::.||.:..::...||:.||...|.....|:|.:|.|.|. |.|....|....|.|
  Fly   157 NWCGFLGDFSTIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCL 221

  Fly   253 GLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGV 317
            ||:....:...|..||......|:|||::...:|::.||.:||:.......||:.|:.:|::|..
  Fly   222 GLIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRR 286

  Fly   318 RV-NRDF------VERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSV 375
            :| ::||      .|:..||         ..:...|..:||:.:.|.||.....:.||:......
  Fly   287 QVADKDFKDFRIYCEQHYRK---------DKNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPC 342

  Fly   376 YVGLSYYAPALGGDEIWNFFLAGAVELPT--YLLLWPGL--SYFGRRWILFISMLVGGVACVATF 436
            |..::.....||......|.| .|:.||.  ||   .||  ...||:......|.:.|:..||..
  Fly   343 YNTIARNVEGLGISPFIMFSL-NALTLPPSGYL---QGLLQDRMGRKATAVGWMAITGIFAVAAG 403

  Fly   437 LY------PDITLL--LYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPM 493
            |.      .::.||  |....:.|:|.:.......::||.||.|||.|::...|.......:.|.
  Fly   404 LVISQGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPY 468

  Fly   494 INHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGE 539
            |.|:|......|.|::|.|.:.|.:..||||||||:.||.:|.|||
  Fly   469 ILHLGTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	111/415 (27%)
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	140/547 (26%)
CG14855	NP_650390.2	MFS	127..499	CDD:119392	104/384 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458526
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990