DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and CG44098

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster

Alignment Length:	593	Identity:	146/593 - (24%)
Similarity:	242/593 - (40%)	Gaps:	115/593 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQH---FCRVPELEPWTQDYVQL 65
            |.|.:..|.:|.:|...:..:.| ..:|.::.....:|.|..|:|   ||:.|. ....|:..|.
  Fly   207 DAVGQITGPWGKWQLRTVLLIFL-CKIPSSWFMACIIFTAPAPRHGEFFCKPPH-TIGAQNQTQW 269

  Fly    66 VKNLSIPRNRNGAYAE-----CSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPC 125
            :| :|.|:.......|     |::|.........|..|.......|...:.|.:    .:.|:||
  Fly   270 IK-VSHPQKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHR----NSNVIPC 329

  Fly   126 QHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLA--LVVFGV--GGLLGNYVFGYL----VDLWGRR 182
            ....|  :|.|.| ||.:::|||.|..||::.  ..:|||  ||:|.|.:..|.    |.|:|..
  Fly   330 TEFQH--ESDYHS-VVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMI 391

  Fly   183 PSFY---------AYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPER 238
            ...:         :|.|.....|.::......||                |...::| ::.|.:.
  Fly   392 TQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYT----------------AGGQIMA-DITGGKY 439

  Fly   239 RVFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRR 303
            |...:.:....:|:|:::|.||......|..|.:|:|.|.::|...:..:|:|||||:|.|:|:.
  Fly   440 RTCVSTLFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILIYLWQWIPDSPRWLIARGRTQD 504

  Fly   304 AIKILKVMARVNGVRVN--RDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIIT 366
            |.|||.....|||...|  .|..::|:.:      |:|........|...:::|....|..:.:.
  Fly   505 AKKILLECVEVNGTGYNLPHDIDQQLELQ------AQTAMDAPPPSGWWSMWKGERAVRHIVCVH 563

  Fly   367 LIWFANTSVYVGLSYYAPALGGDEIW-NFFLAGAVEL------------PTYLLLWPGL------ 412
            |.|.....||.|:.....:...|.:: |.|.||..|:            .|...||.||
  Fly   564 LAWSLYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAG 628

  Fly   413 --SYFGRRWILFISMLVGGVACVATFLYPDITLLLYC---VGKMGISSSFVVLPLMASELYPTVV 472
              :|.|  |::....::|        |.|::.||: |   |.||.||::..:|.....||.....
  Fly   629 CIAYCG--WLVPKPSVIG--------LDPNVALLM-CSAMVSKMAISTTLSILTTCTVELVSDDK 682

  Fly   473 RGLGMSFSSV---------ISMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLL--PET 526
            :.: .|||::         ...:|..|:     .||   ::|.....:|.||||..:.|:  |.|
  Fly   683 KKI-TSFSTICWARFWLLGAPFIGSTVV-----FGQ---LIPQTAFASLAILGGLCTSLISSPRT 738

  Fly   527 RNRNLPQT 534
            ...:.|.:
  Fly   739 HPISRPSS 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	114/449 (25%)
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	140/568 (25%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	103/422 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940