DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Balat and CG7458

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	159/560 - (28%)
Similarity:	261/560 - (46%)	Gaps:	67/560 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DEVLREVGSFGLYQKVIICSVLLPAALPCAFHAY---SQLFIAATPQHFCRVPELEPWTQDYVQL 65
            |.:|..:|.||.||  ||..|||  .:|..|:|:   |.:|.|:|..|.|.||:.:..:..|.:.
  Fly    39 DAILVRIGQFGRYQ--IINYVLL--CVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEED 99

  Fly    66 VKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHGWH 130
            ....:||: :|.|:.:|..|:.|.:|.:.  .|..|..  :...::...:..:|     |...:.
  Fly   100 WLGFTIPK-KNSAWDDCHRYAANISDAIS--GYTDPSG--QYCLKEYFTITSET-----CGRDFK 154

  Fly   131 YDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIA 195
            :...  ..|:..|:.:.|:..:.:::...:..||..:|..:.||..|.:|||         .::|
  Fly   155 FRDE--EKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRR---------TMLA 208

  Fly   196 CAASAFAW---------NYYTWLGLRFV---VGLTVPAILASPYVLAIELVGPERRVFCTIVSNI 248
            .|.|..|.         ||..:|...|:   ||.|   :..:.::||||||||:|||....:..|
  Fly   209 VAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGST---LFPTAFLLAIELVGPKRRVAAATIITI 270

  Fly   249 AYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMAR 313
            .|:||...|..:...|:.||.|...:..|.::.....::||||.|||::.|...:|..:|:..||
  Fly   271 FYALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAAR 335

  Fly   314 VNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLI------ITLIWFAN 372
            :|    .|...|.....|:.:...:...:..:.|        |.||.....      ..|.||.:
  Fly   336 IN----QRPLPEEQLNDLLTSNRQKLSQANESQY--------PIMRAVVFFSLRIANCCLCWFTH 388

  Fly   373 TSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISML-----VGGVAC 432
            |.:.:|||..:..|||::..||.|.|.:::|..||....:...|||..|..|||     :|..|.
  Fly   389 TLIALGLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAA 453

  Fly   433 VATFLYPDITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHM 497
            |....|.. :|.|:.:||:.|:.||.:|....||::||.||...:|..|::..:|.::.|....:
  Fly   454 VPADNYAG-SLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLL 517

  Fly   498 GQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEE 537
            .:..:..|.|:.....::.||.:|..|||.::.||.|:||
  Fly   518 AKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEE 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	115/418 (28%)
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	154/548 (28%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	115/407 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458523
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.990