Protein Alignment Balat and SLC22A25

DIOPT Version :9

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Alignment Length: 619
• Identity: 155/619 - (25%)
• Similarity: 264/619 - (42%)
• Gaps: 92/619 - (14%)

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQL--FIAATPQHFC--------RVPEL 55
            |.|.::|.:||..|.:|  |:..|.|.......:| .:||  |.|....|.|        .:|:.
Human     1 MAFQDLLDQVGGLGRFQ--ILQMVFLIMFNVIVYH-QTQLENFAAFILDHRCWVHILDNDTIPDN 62

  Fly    56 EPWTQDYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTT 120
            :|.|.....|:: :|||.:.|....:|..:            ..|...|:..........:|||.
Human    63 DPGTLSQDALLR-ISIPFDSNLRPEKCRRF------------VHPQWKLIHLNGTFPNTSEPDTE 114

  Fly   121 QVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVD-------- 177
               ||..||.||:|.:.||:|.:|:|||:...|.::|..:|..|.::|..::|:|.|
Human   115 ---PCVDGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRKPLSSPN 176

  Fly   178 ---------------------LW-GRRPSF---YAYLLLEIIACAASAFAWNYYTWLGLRFVVGL 217
                                 .| ||:  |   ::||.|.|:...| |||.....:..|||:.|.
Human   177 HVSTDCDEGLEVPIAIHQHHVFWFGRK--FVLRWSYLQLAIVGTCA-AFAPTILVYCSLRFLAGA 238

  Fly   218 TVPAILASPYVLAIELVGPERRVFCTIVSNI---AYSLGLVVLAGVIYIVRDWRELSLAVSMPLL 279
            ...:|:.:..:|.:|.:..:   ||.:...:   |.|:|.:.|..:.:::||...|.|.:|.|..
Human   239 ATFSIIVNTVLLIVEWITHQ---FCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCF 300

  Fly   280 MLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFVERLQRKLVITRAAETKSSMT 344
            :.|.....|.||.|||:...|....:|.|:..|..||::...|.:  ....|..|...|.:::..
Human   301 VFFLFSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAEDIL--TMEVLKSTMKQELEAAQK 363

  Fly   345 THYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLW 409
            .| .:.:|.|.||:.::...::.:.||:|..:.||:.:...||.:......|.|||.|....:..
Human   364 KH-SLCELLRIPNICKRICFLSFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAP 427

  Fly   410 PGLSYFGRRWILFISMLVGGVACVATFLYPD----ITLLLYCVGKMGISSSFVVLPLMASELYPT 470
            ..|::..||....:.|.:.....:|....|.    :.::|..:|....|..........:||.|:
Human   428 WALNHMSRRLSQMLLMFLLATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPS 492

  Fly   471 VVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTL 535
            ::||.....:...:.:|..:..::..:......||.|:.|...||.|...||||||||:.|..::
Human   493 IIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAILSGLVVLLLPETRNQPLLDSI 557

  Fly   536 EEGEAVPLSFLLCCCVESERKPNNIRASPKKRIL 569
            ::             ||:| ..|::.|..:..:|
Human   558 QD-------------VENE-GVNSLAAPQRSSVL 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	109/435 (25%)
SLC22A25	XP_016873173.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153677
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5187
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.890