DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Balat and CG42269

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	552	Identity:	194/552 - (35%)
Similarity:	296/552 - (53%)	Gaps:	45/552 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDEVLREVGSFGLYQKVI-ICSVLLPAALPCAFHAYSQLFIAATP-QHFCRVPELEPWTQDYV 63
            ||||::|..:|.||.|||:: ||  ::|.:...||..:||:|:...| ||:|.||||:...   |
  Fly    70 MDFDDILPLIGEFGRYQKLLFIC--MIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDGLD---V 129

  Fly    64 QLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHG 128
            :....||||.. ||.|..|.||..|||||:               |:..:...|...| |.|:||
  Fly   130 EARLALSIPMT-NGEYNNCYMYDVNYTDIL---------------AQGKVMADPKWPQ-VKCRHG 177

  Fly   129 WHYD-KSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLE 192
            |.|: ..|..:||..|.|.|||.:.|.|.|..:|.:|.::|..:||::.|.:||.|:.....::.
  Fly   178 WSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMG 242

  Fly   193 IIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLV-V 256
            ::|...:||..|::.:..:||.||..........|:|.:|.|||:.|.|...:|...:..|.. :
  Fly   243 LLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACL 307

  Fly   257 LAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNG----- 316
            |..:.|.:.||:.|::..|.|||:.....||:|||.|||::.||..:|:.|||.:.:.||
  Fly   308 LPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPP 372

  Fly   317 --VRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGL 379
              .::..|..:|:|.          :.:....|.:||||:.|.:||.||::.:||.|.:.|:.|.
  Fly   373 QTYQIFTDSCKRMQE----------QEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGH 427

  Fly   380 SYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGV-ACVATFLYPDI-T 442
            .....:||.|..:.|.||...|||...||...|..|||||:...||::.|| :.:||.:...| :
  Fly   428 VRNVGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYS 492

  Fly   443 LLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLI 507
            ..|..:|:..::.|:.:....|:|:.|||||...::|..::..|..|:.|.:.::......||||
  Fly   493 AALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLI 557

  Fly   508 VMGALLILGGFASLLLPETRNRNLPQTLEEGE 539
            ::|.|.|:||..:||||||.|..|||||.:||
  Fly   558 ILGILGIIGGLLALLLPETLNHVLPQTLSDGE 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	133/406 (33%)
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	166/503 (33%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	109/348 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458535
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.890