DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and CG10486

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster

Alignment Length:	579	Identity:	169/579 - (29%)
Similarity:	293/579 - (50%)	Gaps:	58/579 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAAT-PQHFCRVPELEPWTQDYVQ 64
            :|||::|..:|.||.:| :.:...::|.....||....|:|:..| |:::|.||||   ....|:
  Fly    94 IDFDDLLPMIGQFGRFQ-IRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPEL---LHTPVE 154

  Fly    65 LVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHGW 129
            |.|.||||:.::|:|:.|.||:.|||.|              ..||:.......:...:||:.|:
  Fly   155 LRKELSIPKEKDGSYSRCRMYNTNYTKI--------------HFAENPSAYINTSLPTIPCKKGY 205

  Fly   130 HYD---KSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLL 191
            .::   ::..|:|:  |:..:||.....|.|.::|.:|.:||...:|:..|..||..:..:...|
  Fly   206 VFEQEGRAFESATM--EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFL 268

  Fly   192 EIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIA----YSL 252
            .::...|::.:.:::|:...||:||.:........|:|.:|.|||:.|   |:|:|::    ||.
  Fly   269 ALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYR---TLVANLSLALFYSP 330

  Fly   253 GLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGV 317
            ..:|:..:.....:||..|...|:|:::....|.:||||.|||::||:..:|::|||.:..||..
  Fly   331 FTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKK 395

  Fly   318 RVNRDFVERLQRKLVITRAAETKSSMTTHY---------GILDLFRGPNMRRKTLIITLIWFANT 373
            :|:::.::..:            :|.|..|         .:|.:|:...|.|..:::.|||.:.:
  Fly   396 QVSKEILDLFE------------ASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSIS 448

  Fly   374 SVYVGLSYYAPALGGDEIWNFF-LAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACV--AT 435
            .||.|....|..|..:.|:.|| :|.|.|||..:|:...|...||||..|....:.||..:  |:
  Fly   449 LVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGAS 513

  Fly   436 FLYPDITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQ 500
            |.......:....|:...:..:.:....|:|:.|||||..|::|...:..|..::.|.:.::.::
  Fly   514 FQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKK 578

  Fly   501 MLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLS---FLLCCCVESERK 556
            .|...|||:|||.|.||..:|.||||.|..||:||.:|.....:   :.:.||....||
  Fly   579 SLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRK 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	115/414 (28%)
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	158/542 (29%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	109/385 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458536
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.890