DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Balat and CG4324

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001286807.1	Gene:	CG4324 / 37830	FlyBaseID:	FBgn0034956	Length:	478	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	117/500 - (23%)
Similarity:	205/500 - (41%)	Gaps:	110/500 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 YLEYRP----------PPDLLRQQAE-DLLKLQPDTTQVV-----PCQHGWHYDK---------- 133
            ||...|          |.|:.....| ..:.:.||.|..|     ....||.:.|
  Fly     3 YLNNEPAALPSPANLAPRDVHSSTLELKTVSINPDDTYTVQQAINAFGFGWFHVKLSLLVGLCWM 67

  Fly   134 ---------SIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAY- 188
                     ||...::..|||:...:...||  .||| :|.:|.:..:..|.:.:||:.:...:
  Fly    68 SDSMEMAILSILGPSLFCEWNVTKFQQASVT--TVVF-LGMMLSSSFWTQLSNRYGRKSALTLFG 129

  Fly   189 ---LLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAY 250
               :|..|::..|.::||    .|.||.:||..:..:..| ..|..|.:..:.:..|.::.:..:
  Fly   130 VLLVLYSILSSVAPSYAW----LLTLRGLVGFAIGCVPQS-VTLYAEFLPTKHKGKCVVLMDCFW 189

  Fly   251 SLGL---VVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFV-LPESPRWLMAVGKTRRAIKILKVM 311
            :||.   ||||.|:|....||.| ||:|...|::|:.... |.||.|:....|...:|||:|:.:
  Fly   190 ALGACFEVVLALVVYPYYGWRGL-LALSATPLLIFTILSPWLSESARYYSYNGHNDKAIKVLEQI 253

  Fly   312 ARVNGVRVNRDFVERLQRKLVITR-AAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSV 375
            |..|            :|.:::.| .|:.:.|....:..|   ..|::.|.|:::..:|.|:...
  Fly   254 AHNN------------KRHMLMGRLMADDEPSCAESFRSL---LSPSLYRTTILLWFLWLASAFC 303

  Fly   376 YVGLSYYAPAL--------GGDEIWNFFLAGAVELPTYLLLW------PGL-------SYFGRRW 419
            |.||......|        ..:|...|..:..::     |||      ||:       ..||::.
  Fly   304 YYGLVLVTTELLVARNKESHPNECVTFMTSDFMD-----LLWITLSEFPGILLTIKVVKLFGKKK 363

  Fly   420 ILFISMLVGGVACVATFLYPD------ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMS 478
            .:.:..| ..|.|....:..:      :||.   :.:..||..|..:.:...|:||..:|.:|:|
  Fly   364 TIVLQYL-ALVLCTLVLMSVESRFSTSVTLF---IARGTISGIFQAIYVYTPEIYPAALRSVGVS 424

  Fly   479 FSSVISMVGPIVIPMINHMGQQMLV--LPLIVMGALLILGGFASL 521
            ..||::.:|.::.|.:    .|:|:  ..:..|....|:|..||:
  Fly   425 GCSVLARLGAMLTPFV----AQVLMDSSRIQAMSTYAIVGLLASI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	107/450 (24%)
CG4324	NP_001286807.1	2A0119	10..476	CDD:273328	114/492 (23%)
CG4324	NP_001286807.1	MFS	60..471	CDD:119392	104/442 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458143
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.970