Protein Alignment Balat and Slc22a22

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 569
• Identity: 148/569 - (26%)
• Similarity: 256/569 - (44%)
• Gaps: 68/569 - (11%)

  Fly     1 MDFDEVLREVGSFGLYQ--KVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYV 63
            |.|||:|..||..|.:|  .:::.::|   ::..:.|...:.|.||.|.|.|.|..|:. ::..:
  Rat     1 MAFDEILHHVGDRGRFQIWMIVVLNIL---SMVSSLHDVIENFTAAIPAHHCSVNLLDT-SRSEI 61

  Fly    64 QLVKNL--------SIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTT 120
            .:..||        |||...|....:|..:.......:       ..::....:.:|
  Rat    62 SMAMNLTTEAMMKVSIPMGPNQKPEQCRRFRHPQWQFI-------DSNISTSNSTEL-------- 111

  Fly   121 QVVPCQHGWHYDKSIYSSTVVQEWNLVCD-RSFLVTLALVVFGVGGLLGNYV----FGYLVDLWG 180
            :..||..||.||.|:::||:|.||:|||| :||.......     .|.|::|    .|.:.|.:|
  Rat   112 ETEPCLDGWTYDHSVFTSTIVTEWDLVCDFQSFKYYAQAT-----SLAGHFVAAPFCGIISDRFG 171

  Fly   181 RRP-SFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTI 244
            |:| ..|..|...|:. ...||..|:..:..|||:...:...:..:..:|.:|....:......:
  Rat   172 RKPLLMYCSLAYGILG-TCCAFVPNFSLYCVLRFLSSASASTVGMNCLILVLEETSVQWHATVIV 235

  Fly   245 VSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILK 309
            :|.:..|.||..|.|:.|::.||..:.|..::|..:.|..|..:|||.||||..|||.:|:|.|:
  Rat   236 LSGLFSSTGLAGLGGLAYVLSDWHLIQLTSALPYFIFFILFCWVPESARWLMITGKTDQALKELQ 300

  Fly   310 VMARVNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTS 374
            .:|.:||   .:|..:.|..:.:.::..|...|...|:.|.|:...|.:|:..|..:.:.||...
  Rat   301 RIASING---KKDIAQNLTTEDLRSKVKEDVCSTVKHFSIKDIIINPMIRKIVLCYSSVLFAELF 362

  Fly   375 VYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYF------GRRWILFISMLVGGVACV 433
            ...||......||.:......|.|.:::|:     ..|:||      .|..|.|:....||...:
  Rat   363 SIFGLLLDVHMLGKNIFVTQILLGVIDIPS-----KSLTYFILRNVRRRPLIAFLLFATGGCITI 422

  Fly   434 ATFLYPD---ITLLLYCVGKMGISSSFV-VLPLMASELYPTVVR----GLGMSFSSVISMVGPIV 490
            ..||..|   :.|.::.:|| |..::|: :.....:||.|..:|    |:.:|.:.:.|::..:.
  Rat   423 TMFLSEDMYVLRLAIFILGK-GCFAAFISINTAYCNELSPVPLRSTLNGIYISVARLASVLSALT 486

  Fly   491 IPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGE 539
            :....:    .::||:|..|.|.|:.......||||.|..:..|:::.|
  Rat   487 LVTRKY----FVLLPMIFCGVLPIVATINIYFLPETFNHPITDTIKDME 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	112/415 (27%)
Slc22a22	NP_001013969.1	MFS_OAT	109..516	CDD:340932	115/433 (27%)