Protein Alignment Balat and Slc22a3

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_062103.1
• Gene: Slc22a3 / 29504
• RGDID: 3701
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 172/582 - (29%)
• Similarity: 291/582 - (50%)
• Gaps: 57/582 - (9%)

  Fly     3 FDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHF-CRVP------ELEPWT- 59
            ||:.||:.|.||.:|:.:...:.| ..:..||.....:|:.:.|.:: ||.|      |...|:
  Rat     4 FDQALRKAGEFGRFQRRVFLLLCL-TGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSP 67

  Fly    60 -QDYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVV 123
             :::......|.:|..|.| ...|..|....|:....|...|           |......:..:|
  Rat    68 EEEWNLTTPELHVPAERRG-QGHCHRYLLEDTNTSSELSCDP-----------LAAFPNRSAPLV 120

  Fly   124 PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAY 188
            ||...|.|.::  .||:|.:::|||..::::.|...:..:|.|.|.:..||..|.:||
  Rat   121 PCSGDWRYVET--HSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGR------- 176

  Fly   189 LLLEIIAC-------AASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVS 246
            |::.:|:|       ...|||.|:..::..||:.|:.......:.:|:..|:||.::|....||.
  Rat   177 LIVYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVI 241

  Fly   247 NIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVM 311
            .:.::||:::|.|:.|....|:.:.||:|:|..:....::|:|||||||:...:..:|::||:.:
  Rat   242 QMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRV 306

  Fly   312 ARVNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVY 376
            |:.||..::.::.|       ||...|..|:.:    .|||.|.|.||:.|||:...||.:..||
  Rat   307 AKCNGKHLSSNYSE-------ITVTDEEVSNPS----CLDLVRTPQMRKCTLILMFAWFTSAVVY 360

  Fly   377 VGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYPD- 440
            .||......:||:...:||::|.||||..||:...:...|||.....|.:|.||:|:.|...|:
  Rat   361 QGLVMRLGLIGGNLYMDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEG 425

  Fly   441 ---ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIP-MINHMGQQM 501
               :...:..:|::||:.:|.::.|:.||||||.:|..|:|..|.:...|.|:.| ::..:....
  Rat   426 IPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIW 490

  Fly   502 LVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNNIRAS 563
            |.||||:.|.|..:.|...:|||||:...||:|:|:.|.:..|.|..|   ..:|...:..|
  Rat   491 LELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGSSQLHQC---GRKKKTQVSTS 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	127/407 (31%)
Slc22a3	NP_062103.1	2A0119	12..523	CDD:273328	160/543 (29%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O75751	284..288		3/3 (100%)