Protein Alignment Balat and Slc22a2

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_113772.1
• Gene: Slc22a2 / 29503
• RGDID: 61936
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 190/600 - (31%)
• Similarity: 296/600 - (49%)
• Gaps: 81/600 - (13%)

  Fly     4 DEVLREVGSFGLYQKVIICSVLLPAALPCAFHA--YSQLFIAATPQHFCRVPELEP------WTQ 60
            |::|..:|.|.|:||.   :..|.|.|..||..  ...:|:..||.|.|..|....      |:|
  Rat     5 DDILEHIGEFHLFQKQ---TFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQRCGWSQ 66

  Fly    61 ----DYVQLVKNLSIPRNRNGAYAECSMY----SRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQP 117
                :|.  |..|. |.:.....::|..|    :::..|.|                :.|..|..
  Rat    67 AEELNYT--VPGLG-PSDEASFLSQCMRYEVDWNQSTLDCV----------------DPLSSLAA 112

  Fly   118 DTTQVV--PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWG 180
            |..|:.  ||:|||.|:..  .|::|.|:||||..|:::.|...|..||..:|..:.|||.|.:|
  Rat   113 DRNQLPLGPCEHGWVYNTP--GSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFG 175

  Fly   181 RRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIV 245
            |:......:|:..|:.|..|.:.||...|..||:.||...|.....|:|..|.||...|....|.
  Rat   176 RKFCLLVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGIC 240

  Fly   246 SNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKV 310
            ..||:::||::||||.|::.:||.|..||::|.......|:.:|||||||::..|..:|:||:|.
  Rat   241 YQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKH 305

  Fly   311 MARVNGVRV-----NRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWF 370
            :|:.||..|     |....|...:||        |.|      ||||.|.|.:|:.|||:...||
  Rat   306 IAKKNGKSVPVSLQNLTPDEDAGKKL--------KPS------ILDLVRTPQIRKHTLILMYNWF 356

  Fly   371 ANTSVYVGLSYYAPALGGDEIW-NFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVA 434
            .::.:|.||..:. .|.||.|: :||.:..||.|...::...:...|||:...:|.:|.|.||:|
  Rat   357 TSSVLYQGLIMHM-GLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLA 420

  Fly   435 TFLYPD----ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIP-MI 494
            :...||    :.:.:.|:|:|||:.::.::.|:.:|||||.:|.||:...|.:..:|.|:.| ::
  Rat   421 SVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGIITPFLV 485

  Fly   495 NHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAV--PLSFLLCCCVESERKP 557
            ..:....:..||:|...:.::.|...||||||:.:.||:|:|:.|.:  |.        :.|||.
  Rat   486 YRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPR--------KKERKE 542

  Fly   558 NNIRASPKKRILPEA 572
            |   ..|.:...|.|
  Rat   543 N---LPPSQASRPSA 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	138/406 (34%)
Slc22a2	NP_113772.1	2A0119	12..525	CDD:273328	177/551 (32%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		3/3 (100%)