Protein Alignment Balat and Slc22a20

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001381833.1
• Gene: Slc22a20 / 293686
• RGDID: 1311460
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 596
• Identity: 182/596 - (30%)
• Similarity: 297/596 - (49%)
• Gaps: 67/596 - (11%)

  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQL 65
            |.|.::|..:|..|.:|.|....:|||..| .|.|.:.|.|.||.|.|.|:.|      .:|.:.
  Rat     1 MAFTDLLDALGGVGRFQLVYTALLLLPCGL-LACHTFLQNFTAAAPPHHCQHP------ANYTEA 58

  Fly    66 VKN-------LSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQ-- 121
            ..|       .:||.|::|....|..|:.             |...|         |:|:|:.
  Rat    59 TTNDSGAWLRATIPLNQHGVPEPCQRYTE-------------PQWAL---------LEPNTSSHG 101

  Fly   122 --VVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRR-P 183
              ...|:.||.||:||:.||:|.||:|||:...|..||..::..|.|:|..:||.|.|..||: |
  Rat   102 VATEGCKDGWVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGSLADRLGRKAP 166

  Fly   184 SFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNI 248
            ..::||.| .::.|.:|:..::..:...||::|:|...|:.:...|.:|.:....|....|:...
  Rat   167 LVWSYLQL-AVSGAVTAYVGSFSAYCIFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGF 230

  Fly   249 AYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMAR 313
            :::||.::||||.|::|.||.|..|||.|.|:.|...:.||||.|||:..||.::|::.|:.:|.
  Rat   231 SFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKVAM 295

  Fly   314 VNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVG 378
            :||.:...   |||..::|.:......:|:.|...||||||.|.:|:.|..:.::||:|:..|.|
  Rat   296 MNGRKAEG---ERLTIEVVSSYIQNEFASVRTSNSILDLFRTPGIRKVTCCLMMVWFSNSVAYYG 357

  Fly   379 LSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYPD--- 440
            |:......|........|.|.:::|..|:....:.|.|||..:...:::.|:..:|....|:
  Rat   358 LAMDLQKFGLSIYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVPEDLQ 422

  Fly   441 -ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVL 504
             :..:...:||..::|||:.:.|...|||||.:|.:||.|:||.:.:|.:..|:|..:|:...||
  Rat   423 TLRTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVL 487

  Fly   505 PLIVMGALLILGGFASL-LLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNNIRASPKKR- 567
            |.:..||..:|.|.|.: .|.||||..|.:|:             ..:||..|..:.:...:::
  Rat   488 PPVSFGATSVLAGMAVICFLTETRNVPLVETI-------------AAMESRVKEGHSKRDTEQKN 539

  Fly   568 ---ILPEAGTP 575
               .|.:.|.|
  Rat   540 EEISLQQLGAP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	134/401 (33%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	135/408 (33%)