Protein Alignment Balat and Slc22a3

DIOPT Version :10

• Sequence 1: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 582
• Identity: 171/582 - (29%)
• Similarity: 290/582 - (49%)
• Gaps: 57/582 - (9%)

  Fly     3 FDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHF-CRVP------ELEPWT- 59
            ||:.||:.|.||.:|:.:...:.| ..:..||.....:|:.:.|.:: ||.|      |...|:
Mouse     4 FDQALRKAGEFGRFQRRVFLLLCL-TGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSP 67

  Fly    60 -QDYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVV 123
             :::......|.:|..|.| ...|..|....|:....|...|           |......:..:|
Mouse    68 EEEWNLTTPELHVPAERRG-QGHCHRYLLEATNTSSELSCDP-----------LTAFPNRSAPLV 120

  Fly   124 PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAY 188
            .|...|.|.::  .||:|.:::|||..::::.|...:..:|.|.|.:..||..|.:||
Mouse   121 SCSGDWRYVET--HSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGR------- 176

  Fly   189 LLLEIIAC-------AASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVS 246
            |::.:|:|       ...|||.|:..::..||:.|:.......:.:|:..|:||.::|....||.
Mouse   177 LIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVI 241

  Fly   247 NIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVM 311
            .:.::||:::|.|:.|....|:.:.||:|:|..:....::|:|||||||:...:..:|::||:.:
Mouse   242 QMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRV 306

  Fly   312 ARVNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVY 376
            |:.||..::.::.|       ||...|..|:.:    .|||.|.|.||:.|||:...||.:..||
Mouse   307 AKCNGKHLSSNYSE-------ITVTDEEVSNPS----CLDLVRTPQMRKCTLILMFAWFTSAVVY 360

  Fly   377 VGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYPD- 440
            .||......:||:...:||::|.||||..||:...:...|||.....|.:|.||:|:.|...|:
Mouse   361 QGLVMRLGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEG 425

  Fly   441 ---ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIP-MINHMGQQM 501
               :...:..:|::||:.:|.::.|:.||||||.:|..|:|..|.:...|.|:.| ::..:....
Mouse   426 IPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIW 490

  Fly   502 LVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNNIRAS 563
            |.||||:.|.|..:.|...:|||||:...||:|:|:.|.:..|.|..|   ..:|...:..|
Mouse   491 LELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGSSQLHQC---GRKKKTQVSTS 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	127/407 (31%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	159/543 (29%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O75751	284..288		3/3 (100%)