DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Balat and sv2c

DIOPT Version :9

Sequence 1:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_002934873.1	Gene:	sv2c / 100490137	XenbaseID:	XB-GENE-960877	Length:	725	Species:	Xenopus tropicalis

Alignment Length:	640	Identity:	120/640 - (18%)
Similarity:	212/640 - (33%)	Gaps:	234/640 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 EYRPPPDLLRQQAEDLLKLQPDTTQVV-PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVV 160
            ||:...:|..::..|..:|......:: .|.||..            :|.|.    |::.:||:.
Frog   114 EYKDRRELETERKADEEELAQQYELIIQECGHGRF------------QWTLF----FVLGMALMA 162

  Fly   161 FGV--------------------------------GGLLGNYVFGYLVDLWGRRPS--------- 184
            .||                                |.::|.:.:|.|.|..||:.|
Frog   163 DGVEVFVVGFVLPSAETDMCIPDSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNG 227

  Fly   185 FYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERR--------VF 241
            |:|:|         |:|...|..:|..|.:.|..:...|.:.:....|::..|:|        :|
Frog   228 FFAFL---------SSFVQGYGLFLVCRLLSGFGIGGALPTAFSYFSEVLAREKRGEHLSWLCMF 283

  Fly   242 CTI----VSNIAYSL----GLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAV 298
            ..|    .|.:|:::    |.....|..|....||...:..::|.:........:|||||:|:..
Frog   284 WMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSAVVALTFMPESPRFLLET 348

  Fly   299 GKTRRAIKILKVM----ARVNGVRVNRDFVERLQRKLVITRAAETKSS------------MTTHY 347
            ||...|..|||.:    .|..|.......|:|::....|....|.:|.            .|..|
Frog   349 GKHDEAWMILKQIHDTNMRARGEPEKVFTVQRIKTPKQIDELIEIESDTGTWYKRCFVRIRTEFY 413

  Fly   348 GI----LDLFRGPNMRRKTLIITLIWFANTSVYVGLSYY----APALGGDEI------------- 391
            ||    :..|..| ::..|:.:|::|...:..|.|||.:    ...|..||.
Frog   414 GIWLTFMRCFEYP-VKDNTIKLTIVWLTLSFGYYGLSVWFSDVIKHLQADEYASRVKRFNGSTIA 477

  Fly   392 ---WNFFLAGAV-----------------------------------ELPTY------------- 405
               :|:.|...:                                   .:.||
Frog   478 DYKFNYTLENQIHKNAVFINDRFISMKFKSVVFQDSLFERCYFEDVTSINTYFRNCTLIDTHFVN 542

  Fly   406 ----------------------------------------------LLLWPG-------LSYFGR 417
                                                          |.:.||       :...||
Frog   543 TDLEKYKFTDSQTINCTFTIPKIGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDKIGR 607

  Fly   418 RWILFISMLVGGVACVATFLYPDITLL--LYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFS 480
            ..:|..||::.|::|...:.....:::  :.||......|::..|.::..|||||..|..|..|.
Frog   608 LTMLGGSMVLSGISCFLLWFGTSESMMVGMLCVYNGLTISAWNSLDVVTVELYPTDKRATGFGFL 672

  Fly   481 SVI----SMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNL 531
            :.:    :::|.::...:..:.:   .:|:::..|:|:.||...|.||:|||:.|
Frog   673 NALCKGAAVLGNLIFGSLVGITK---AIPILLASAVLVGGGLVGLRLPDTRNQVL 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	107/599 (18%)
sv2c	XP_002934873.1	synapt_SV2	1..725	CDD:130366	120/640 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030