DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and Pi16

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_076223.3	Gene:	Pi16 / 74116	MGIID:	1921366	Length:	498	Species:	Mus musculus

Alignment Length:	294	Identity:	71/294 - (24%)
Similarity:	107/294 - (36%)	Gaps:	124/294 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PPLLLLLMLLGQQLQAFDYCDPTLCPGPERHIACNNFGALADICSPDAHIVRITTA-----RRTM 66
            |||||||:|              :..||                         |||     ::||
Mouse    13 PPLLLLLLL--------------IATGP-------------------------TTALTEDEKQTM 38

  Fly    67 ILNEL-NEYRDRIARGDLMGFSPATRMATLQWDQELASFAELNVKRCALVNDHCRNSEQFR---N 127
            :  :| |:||.:::       .||:.|..::||.|||:||:...::|  |..|  |.|:.|   |
Mouse    39 V--DLHNQYRAQVS-------PPASDMLQMRWDDELAAFAKAYAQKC--VWGH--NKERGRRGEN 90

  Fly   128 VAQVVAEGGWQGDPLPPSSPSDPPNPEAPIPV-EYHTEDEVIKATLEQMFAEYKECSMRDIIAFS 191
            :..:..||                 .:.|:.| .:|.|.            ||...|    .|..
Mouse    91 LFAITDEG-----------------MDVPLAVGNWHEEH------------EYYNFS----TATC 122

  Fly   192 PPNNRILRLRVSKCIAYFTQLVRDSTTHVGCGI-LRQTKNTTNEAGQSLSSVHQYMTCNFVRTND 255
            .||         :...::||:|...|..:|||. ..:|.....||     ::| .:.||:....:
Mouse   123 DPN---------QMCGHYTQVVWSKTERIGCGSHFCETLQGVEEA-----NIH-LLVCNYEPPGN 172

  Fly   256 VNA-PVYQSGDRPATECRSG-----------RNP 277
            |.. ..||.| .|.::|..|           |||
Mouse   173 VKGRKPYQEG-TPCSQCPLGYSCENSLCEPMRNP 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	47/191 (25%)
Pi16	NP_076223.3	SCP_HrTT-1	35..168	CDD:240186	48/193 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..277		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..407
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	419..467
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920