DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and CRISP2

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	XP_005249406.1	Gene:	CRISP2 / 7180	HGNCID:	12024	Length:	278	Species:	Homo sapiens

Alignment Length:	334	Identity:	68/334 - (20%)
Similarity:	109/334 - (32%)	Gaps:	126/334 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PLLLLLMLLGQQLQAFDYCDPTLCPGPERHIACNNFGALADICSPDAHIVRITTARRTM--ILNE 70
            |:|.|:.:|...|.| :..||.             |.||            :||..:..  |:|:
Human     5 PVLFLVTVLLPSLPA-EGKDPA-------------FTAL------------LTTQLQVQREIVNK 43

  Fly    71 LNEYRDRIARGDLMGFSPATRMATLQWDQELASFAELNVKRCALVNDHCRNSEQFRNVAQVVAEG 135
            .||.|..::       .||:.|..::|.:|:.:.|:....:|.|.:    :..:.|..:....|.
Human    44 HNELRKAVS-------PPASNMLKMEWSREVTTNAQRWANKCTLQH----SDPEDRKTSTRCGEN 97

  Fly   136 GWQGDPLPPSSPSDPPNPEAPIPVEYHTEDEVIKATLEQMFAEYKECSMRDIIAFSPPNNRILRL 200
            .:..        |||.:..:.|...|   ||::                 |.:....|.:
Human    98 LYMS--------SDPTSWSSAIQSWY---DEIL-----------------DFVYGVGPKS----- 129

  Fly   201 RVSKCIAYFTQLVRDSTTHVGCGILRQTKNTTNEAGQSLSSVHQYMTCNFVRT------------ 253
             .:..:.::||||..||..|||||    ....|:.......|.||  |..::|
Human   130 -PNAVVGHYTQLVWYSTYQVGCGI----AYCPNQDSLKYYYVCQY--CPAMKTYLNKREGINVWK 187

  Fly   254 ------------------------NDVNAPVYQSGDRPA---TECRSGRNPVFINLCSVNEIYDS 291
                                    |..|.| ||.|...|   .:|..|   :..|.|...::..:
Human   188 CFLRLRHFQLLRGEQLLTFSGNNMNRKNTP-YQQGTPCAGCPDDCDKG---LCTNSCQYQDLLSN 248

  Fly   292 ----SNLAG 296
                .|.||
Human   249 CDSLKNTAG 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	40/187 (21%)
CRISP2	XP_005249406.1	SCP_CRISP	35..172	CDD:240183	40/187 (21%)
CRISP2	XP_005249406.1	Crisp	224..278	CDD:285731	8/37 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750