DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and Ag5r2

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_524689.2	Gene:	Ag5r2 / 44079	FlyBaseID:	FBgn0020508	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	86/282 - (30%)
Similarity:	130/282 - (46%)	Gaps:	36/282 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLLMLLGQQLQAFDYCDPTLCPGPERHIACNNFGALADICSPDAHIVRITTARRTMILNELNE 73
            ||.:|::.....||.|||...:|.|.. ||||.:.......|..||.::.|....:.:.::..|:
  Fly     5 LLAILIVSLALAQATDYCSSDICNGGS-HIACGHSNWWDSSCPGDAELIDINDDYKWVFVHSHND 68

  Fly    74 YRDRIARGDLMGFSPATRMATLQWDQELASFAELNVKRCALVNDHCRNSEQFRNVAQVVAEGGWQ 138
            .|:.||.|.....:.|.||||::||.|||..|.|||::|.:|:|.|.|::.|:...|.:|...:.
  Fly    69 KRNYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQCNMVHDSCHNTDAFKYSGQNLAWQAYS 133

  Fly   139 GDPLPPSSPSDPPNPEAPIPVEYHTEDEVIKATLEQMFAEYKECSMRDIIAFSPPNNRILRLRVS 203
            || ||              .:.|..::.|      ||:.:....|...|||...|:.     ...
  Fly   134 GD-LP--------------DMGYILDNSV------QMWFDEVHNSNAGIIAGGYPSG-----YNG 172

  Fly   204 KCIAYFTQLVRDSTTHVGCGILRQTKNTTNEAGQSLSSVHQYMTCNFVRTNDVNAPVYQSGDRPA 268
            ..|.:||.::.:..|.:||...|..::..|:.         .:.||:..||.:...:|.|.|..|
  Fly   173 PAIGHFTVMMSERNTRLGCAAARYNRDGWNQV---------LVACNYATTNMIGRQIYSSCDWGA 228

  Fly   269 TECRSGRNPVFINLCSVNEIYD 290
            ..|.||.|..|.||||.:|.||
  Fly   229 QGCGSGTNGEFGNLCSTSEWYD 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	49/185 (26%)
Ag5r2	NP_524689.2	SCP_euk	62..211	CDD:240180	50/183 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440580
Domainoid	1	1.000	41	1.000	Domainoid score	I8510
eggNOG	1	0.900	-	-		E1_COG2340
Homologene	1	1.000	-	-		H77274
Inparanoid	1	1.050	76	1.000	Inparanoid score	I5251
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26030
OrthoDB	1	1.010	-	-		D109749at50557
OrthoFinder	1	1.000	-	-		FOG0000453
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.910