DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and PI16

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	281	Identity:	67/281 - (23%)
Similarity:	101/281 - (35%)	Gaps:	118/281 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PLLLLLMLLGQQLQAFDYCDPTLCPGPERHIACNNFGALADICSPDAHIVRITTARRTMILNEL- 71
            ||||||:               ...||        .|||.|            ..:|.|:  ||
Human    13 PLLLLLV---------------ATTGP--------VGALTD------------EEKRLMV--ELH 40

  Fly    72 NEYRDRIARGDLMGFSP-ATRMATLQWDQELASFAELNVKRCALVNDHCRNSEQFR---NVAQVV 132
            |.||.::        || |:.|..::||:|||:||:...::|  |..|  |.|:.|   |:..:.
Human    41 NLYRAQV--------SPTASDMLHMRWDEELAAFAKAYARQC--VWGH--NKERGRRGENLFAIT 93

  Fly   133 AEGGWQGDPLPPSSPSDPPNPEAPIPV-EYHTEDE---VIKATLEQMFAEYKECSMRDIIAFSPP 193
            .||                 .:.|:.: |:|.|.|   :..||          ||
Human    94 DEG-----------------MDVPLAMEEWHHEREHYNLSAAT----------CS---------- 121

  Fly   194 NNRILRLRVSKCIAYFTQLVRDSTTHVGCGILRQTKNTTNEAGQSLSSVH----QYMTCNFVRTN 254
                    ..:...::||:|...|..:|||         :...:.|..|.    :.:.||:....
Human   122 --------PGQMCGHYTQVVWAKTERIGCG---------SHFCEKLQGVEETNIELLVCNYEPPG 169

  Fly   255 DVNAP-VYQSGDRPATECRSG 274
            :|... .||.| .|.::|.||
Human   170 NVKGKRPYQEG-TPCSQCPSG 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	46/198 (23%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	47/200 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920