DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and vap-2

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	284	Identity:	64/284 - (22%)
Similarity:	105/284 - (36%)	Gaps:	92/284 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LCPGPER------HIACNNFGALADICSPDAHIVRITTARRTMILNELNEYRDRIAR-----GDL 83
            ||..|..      ...|:| ..::|:             .|...|.:.|.||.|:|:     |:.
Worm   290 LCQAPSMVKDDGGSFQCDN-SLVSDV-------------TRNFTLEQHNFYRSRLAKGFEWNGET 340

  Fly    84 MGFSP-ATRMATLQWDQELASFAELNVKRCALVNDHCRNSEQFRNVAQVVAEGGWQGDPLPPSSP 147
            ....| |::|..:::|..|..||:.....|...  |..:.|:..           ||..|..||.
Worm   341 NTSQPKASQMIKMEYDCMLERFAQNWANNCVFA--HSAHYERPN-----------QGQNLYMSSF 392

  Fly   148 SDPPNPEAPIPVEYHTEDEVIKATLEQMFAEYKECSMRDIIAFSPPNNRILRLRV----SKCIAY 208
            |: |:|.:.|    ||       .:|:.:.|.:|        |..|.:.:|...:    .|.|.:
Worm   393 SN-PDPRSLI----HT-------AVEKWWQELEE--------FGTPIDNVLTPELWDLKGKAIGH 437

  Fly   209 FTQLVRDSTTHVGCGILRQTKNTTNEAGQSLSSVHQYMTCNF-VRTNDVNAPVYQSGDRP----- 267
            :||:..|.|..:||||....|.:             |:.|:: ...|..|..:|:.|| |
Worm   438 YTQMAWDRTYRLGCGIANCPKMS-------------YVVCHYGPAGNRKNNKIYEIGD-PCEVDD 488

  Fly   268 ----ATECRSGRNPVFINLCSVNE 287
                .|:|..     ..:||.:::
Worm   489 DCPIGTDCEK-----TTSLCVISK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	48/195 (25%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	48/198 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920