DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	280	Identity:	59/280 - (21%)
Similarity:	85/280 - (30%)	Gaps:	92/280 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLMLLGQQLQAFDYCDPTLCPGPERHIACNNFGALADICSPDAHIVRITTARRTMILNELNEYR 75
            |.|:|||..|.|      ...|..|.....|.:                        :|..||.|
Human    31 LWLLLLGSSLNA------RFLPDEEDVDFINEY------------------------VNLHNELR 65

  Fly    76 -DRIARGDLMGFSPATRMATLQWDQELASFAELNVKRCALV-NDHCRNSEQFRNVAQVVAEGGWQ 138
             |.|.||..:.|        :.||..|:..|....|:|... |.:.::.:........:.|..|.
Human    66 GDVIPRGSNLRF--------MTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENMWV 122

  Fly   139 GDPLPPSSPSDPPNP-EAPIPV-EYHTEDEVIKATLEQMFAEYKECSMRDIIAFSPPNNRILRLR 201
            |          |.|. .|.|.: .:|.|.::..       .|...||
Human   123 G----------PENEFTASIAIRSWHAEKKMYN-------FENGSCS------------------ 152

  Fly   202 VSKCIAYFTQLVRDSTTHVGCGILRQTKNTTNEAGQSLSSVHQYMTCNFVRTNDVNAPVYQSGDR 266
             ..|..|. |||.|.:..|||.:     ...::.|..:.:.  ...||:.....:....|:
Human   153 -GDCSNYI-QLVWDHSYKVGCAV-----TPCSKIGHIIHAA--IFICNYAPGGTLTRRPYE---- 204

  Fly   267 PATEC-RSGRNPVFIN-LCS 284
            |...| |.||.....: |||
Human   205 PGIFCTRCGRRDKCTDFLCS 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	39/189 (21%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	41/218 (19%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750