DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and Crisp3

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_033769.1	Gene:	Crisp3 / 11572	MGIID:	102552	Length:	241	Species:	Mus musculus

Alignment Length:	226	Identity:	40/226 - (17%)
Similarity:	82/226 - (36%)	Gaps:	74/226 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 SPDAHIVRITTARRTM---ILNELNEYRDRIARGDLMGFSPA-TRMATLQWDQELASFAELNVKR 111
            |.:..:.:::|:::::   |:::.|:.|.::        ||: :.:..::|:.:    |::|.::
Mouse    23 SQENSLEKLSTSKKSVQEEIVSKHNQLRRKV--------SPSGSDLLNMEWNYD----AQVNAQQ 75

  Fly   112 CALVNDHCRNSE---QFRNVAQVVAEGGWQGDPLPPSSPSDPPNPEAPIPVEYHTEDEVIKATLE 173
            .|   |.|..|.   :.|.......|..:....|.|.|                       :.::
Mouse    76 RA---DKCTFSHSPIELRTTNLKCGENLFMSSYLVPWS-----------------------SVIQ 114

  Fly   174 QMFAEYKECSMRDIIAFSPPNNRILRLRVSKCIAYFTQLVRDSTTHVGCGILRQTKNTTNEAGQS 238
            ..:.|.|..    |....|..|      || .:.:.||:|..|...|.||:....:|
Mouse   115 GWYNESKGL----IFGVGPKQN------VS-VVGHHTQVVWKSNLQVACGVAECPEN-------- 160

  Fly   239 LSSVHQYMTCNFVRTNDVNAPVYQ-SGDRPA 268
              .:..:..|.:       .||.. ||..|:
Mouse   161 --PLRYFYVCRY-------CPVLNYSGHYPS 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	33/192 (17%)
Crisp3	NP_033769.1	SCP	37..172	CDD:294090	33/200 (17%)
Crisp3	NP_033769.1	Crisp	194..241	CDD:285731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840