DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17575 and crispld2

DIOPT Version :9

Sequence 1:	NP_001188917.1	Gene:	CG17575 / 36414	FlyBaseID:	FBgn0250842	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	XP_003199065.1	Gene:	crispld2 / 100535149	ZFINID:	ZDB-GENE-130131-1	Length:	508	Species:	Danio rerio

Alignment Length:	257	Identity:	58/257 - (22%)
Similarity:	96/257 - (37%)	Gaps:	81/257 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PDAHIVRITTARRTMILNELNEYRDR--------IARGDLMGFSPATRMATLQWDQELASFAELN 108
            |||.:    ..||.:      |:.||        ..||::  :..|:.|..:.||.||...|...
Zfish    46 PDAPV----RTRRAI------EWSDREEILKLHNKLRGEV--YPTASNMEYMIWDDELERSATSW 98

  Fly   109 VKRCALVNDHCRNSEQFRNVAQVVAE--GGWQGDPLPPSSPSDPPNPEAPIPVEYHTE---DEVI 168
            .::|..  :| ...:...::.|.:|.  |.::       ||:            ||.:   |||.
Zfish    99 AEQCQW--EH-GPQDLLMSIGQNLAVHWGRYR-------SPA------------YHVQAWYDEVK 141

  Fly   169 KATLEQMFAEYKECSMRDIIAFSPPNNRILRLRVSKC----IAYFTQLVRDSTTHVGCGI-LRQT 228
            ..|    :....||:     .:.|          .:|    ..::||||..:|..|||.: :...
Zfish   142 DYT----YPYPHECN-----PWCP----------ERCSGPMCTHYTQLVWATTNRVGCAVHVCPR 187

  Fly   229 KNTTNEAGQSLSSVHQYMTCNF-VRTNDVNAPVYQSGDRPATECRSGRNPVFINLCSVNEIY 289
            .|...|..::.    .|:.||: .:.|.:....||.| ||.::|    .|.:..:|..|..|
Zfish   188 MNVWGEIWENA----VYLVCNYSPKGNWIGEAPYQHG-RPCSQC----PPSYGGVCRDNLCY 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17575	NP_001188917.1	SCP_euk	64..250	CDD:240180	42/203 (21%)
crispld2	XP_003199065.1	SCP_euk	61..206	CDD:240180	40/191 (21%)
		LCCL	299..382	CDD:128866
		LCCL	402..495	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850