Protein Alignment Cyp9h1 and ERG11

DIOPT Version :9

• Sequence 1: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 520
• Identity: 114/520 - (21%)
• Similarity: 193/520 - (37%)
• Gaps: 137/520 - (26%)

  Fly    33 GVSHEKPWPLIGNIPLKAMIGGMPVLKKMI-ELHTKHTGSPVYGIYALRDAVFFVRD-PELI--- 92
            |:||....||...|.|..:|   |.:..:: :|           :|:||      :| |.|:
Yeast    18 GLSHFLALPLAQRISLIIII---PFIYNIVWQL-----------LYSLR------KDRPPLVFYW 62

  Fly    93 -------KLIGIKEFDHFVNHNSMHNNIQESILSKSLISLRDG-RWKEM---------------R 134
                   .:.|:|.::.|......:.:|...:|...::::..| :..|.               .
Yeast    63 IPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYA 127

  Fly   135 NILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTRFANDVIATVAFGI 199
            ::.||.|...   ::||...|       .:.||.:..:.|..:...|.|....|.:|
Yeast   128 HLTTPVFGKG---VIYDCPNS-------RLMEQKKFVKGALTKEAFKSYVPLIAEEV-------- 174

  Fly   200 SINSFRRKDNEFFRIGQ----------AMSRISAWSVVKAMLYALFPRLMKVLRIQVLDT----- 249
             ...||  |::.||:.:          ....::.::..:::       |.|.:|.: |||
Yeast   175 -YKYFR--DSKNFRLNERTTGTIDVMVTQPEMTIFTASRSL-------LGKEMRAK-LDTDFAYL 228

  Fly   250 -KNID--------YFSSLVTAAMRYRQE-HKVVRPDMIHLLMEAKQQRLADLSDKS------KDE 298
             .::|        .|.:|.....|.|.. .|.:....:.|:.|.::..  |:.|:.      |:.
Yeast   229 YSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNN--DIQDRDLIDSLMKNS 291

  Fly   299 LYYSEF-TADDLLAQCLLFFFAGFEIIS--SSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQP 360
            .|.... ..|..:|..|:....|.:..|  :|...|.| |...|.||..||||.:.|.:..| :.
Yeast   292 TYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLH-LAERPDVQQELYEEQMRVLDGGK-KE 354

  Fly   361 LTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHH 425
            ||||.|.:|..|:..:.|.||...|..|..|:..:|:.:  .|...:..|.. .||..|.:: |.
Yeast   355 LTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHV--PNTSYVIPAGY-HVLVSPGYT-HL 415

  Fly   426 DPENFEDPEFFNPERF----ADGHALESRV--------------YMPFGVGPRNCIGNRMALMEL 472
            ..|.|.:...||..|:    |..:::...|              |:|||.|...|||...|..:|
Yeast   416 RDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQL 480

  Fly   473  472
            Yeast   481  480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	111/515 (22%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	95/435 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050