DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9h1 and CYP709B2

DIOPT Version :9

Sequence 1:	NP_610820.1	Gene:	Cyp9h1 / 36412	FlyBaseID:	FBgn0033775	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_182218.2	Gene:	CYP709B2 / 819309	AraportID:	AT2G46950	Length:	572	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	133/518 - (25%)
Similarity:	235/518 - (45%)	Gaps:	75/518 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SMIALALFIILLVLLY---------KWSVAKYDVFSERGVSHEKPWPLIGNI--------PLKAM 51
            :::|:||.::::..:|         .|.:::.  |.::|:|..|...|.||:        ..|.|
plant    63 NLLAIALVLLVVPKIYGACRILVWRPWMLSRR--FKKQGISGPKYRILYGNLREIRKMKNEAKLM 125

  Fly    52 I---GGMPVLKKMIELHTKHTGSPVYGIYAL----RDAVFFVRDPELIKLIGIKEFDHFVNHNSM 109
            :   ....::.:::. |.:...|. ||...|    .|....:.|.||.|.|...:|..|....:.
plant   126 VLDPNSNDIVPRVLP-HLQQWKSQ-YGETFLYWQGTDPRLCISDHELAKQILSNKFVFFSKSKTK 188

  Fly   110 HNNIQESILSKSLISLRDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQ---LELS 171
            ...::.|  ...||.:....|...|.||.|||:..|:::|..|:..|:....:..::|   :|..
plant   189 PEILKLS--GNGLIFVNGLDWVRHRRILNPAFSMDKLKLMTQLMVDCTFRMFLEWKKQRNGVETE 251

  Fly   172 QDASIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYALFP 236
            |...|..|    |.|...|:|||.|||.|.    .:..|.|:....:.:..|.::..  ||  ||
plant   252 QFVLISRE----FKRLTADIIATAAFGSSY----AEGIEVFKSQLELQKCCAAALTD--LY--FP 304

  Fly   237 RLMKV-----LRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSK 296
            .:..:     |:|..||.|.......::.|  |...|.|....|::.:::.|..      |::|:
plant   305 GIQYLPTPSNLQIWKLDMKVNSSIKRIIDA--RLTSESKDYGNDLLGIMLTAAS------SNESE 361

  Fly   297 DELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPL 361
            .::     :.|:::.:|..|||||.|..::.|.:.|..|.|:...|::|.||:.  :|..|.:..
plant   362 KKM-----SIDEIIEECKTFFFAGHETTANLLTWSTMLLSLHQDWQEKLREEVF--NECGKDKIP 419

  Fly   362 TYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHD 426
            ..:..:|:|.::.|.:|:||.:.|.::..|...:|:.|.:      ....||..:.:||..:|.|
plant   420 DAETCSKLKLMNTVFMESLRLYGPVLNLLRLASEDMKLGN------LEIPKGTTIILPIAKMHRD 478

  Fly   427 PENF-EDPEFFNPERFADG---HALESRVYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKL 485
            ...: .|.:.|||.|||:|   .|......:.|.:|||.|||...|:||.|:::..:|..|:|
plant   479 KAVWGSDADKFNPMRFANGLSRAANHPNALLAFSMGPRACIGQNFAIMEAKTVLAMILQRFRL 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	125/475 (26%)
CYP709B2	NP_182218.2	p450	89..571	CDD:299894	129/492 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810