DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9h1 and CYP711A1

DIOPT Version :9

Sequence 1:	NP_610820.1	Gene:	Cyp9h1 / 36412	FlyBaseID:	FBgn0033775	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_565617.2	Gene:	CYP711A1 / 817157	AraportID:	AT2G26170	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	129/524 - (24%)
Similarity:	227/524 - (43%)	Gaps:	97/524 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QSMIALALF--IILLVLLYK--WSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIGG--MPVLKKM 61
            :::||...|  :::::.||:  |||.        .|......||:|::||.|..|.  ..||.|.
plant    19 EALIAFLTFAAVVIVIYLYRPSWSVC--------NVPGPTAMPLVGHLPLMAKYGPDVFSVLAKQ 75

  Fly    62 IELHTKHTGSPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNSMHNNIQESIL-SKSLISL 125
            .        .|::.....|..:..:.:.||.:.:|||:|....| .|:.:.|..|.| .|.|...
plant    76 Y--------GPIFRFQMGRQPLIIIAEAELCREVGIKKFKDLPN-RSIPSPISASPLHKKGLFFT 131

  Fly   126 RDGRWKEMRN----ILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTR 186
            ||.||.:|||    :..|:...|.:..|:..|.|.:..           ......::...:.|.:
plant   132 RDKRWSKMRNTILSLYQPSHLTSLIPTMHSFITSATHN-----------LDSKPRDIVFSNLFLK 185

  Fly   187 FANDVIATVAFGISINSFRRK-----------DNEFFRIGQAMSRIS-AWSVVKAMLYAL----F 235
            ...|:|...|||:......:|           :...:...|....:| :.|::..:|..:    |
plant   186 LTTDIIGQAAFGVDFGLSGKKPIKDVEVTDFINQHVYSTTQLKMDLSGSLSIILGLLIPILQEPF 250

  Fly   236 PRLMKVL------RIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDK 294
            .:::|.:      |::..:.:.....:.:|:   :..:|.:....|.:.|:::|::      ||.
plant   251 RQVLKRIPGTMDWRVEKTNARLSGQLNEIVS---KRAKEAETDSKDFLSLILKARE------SDP 306

  Fly   295 SKDELYYSEF----TADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISV-HE 354
            ....::.|::    |.:.|||......|.    :||.|..::..|    .|:.||.:||... :.
plant   307 FAKNIFTSDYISAVTYEHLLAGSATTAFT----LSSVLYLVSGHL----DVEKRLLQEIDGFGNR 363

  Fly   355 ELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIP 419
            :|  .|..:|...|..|||.|:.||:|.:..|....||..:::::   .|..|   .||..:.:.
plant   364 DL--IPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEI---GGYLL---PKGTWVWLA 420

  Fly   420 IFSLHHDPENFEDPEFFNPERFADGHALESR-----VYMPFGVGPRNCIGNRMALMELKSIVYQL 479
            :..|..||:||.:||.|.|||| |.:..|.:     .::|||:|||.|:|.|.||.|:|..:..|
plant   421 LGVLAKDPKNFPEPEKFKPERF-DPNGEEEKHRHPYAFIPFGIGPRACVGQRFALQEIKLTLLHL 484

  Fly   480 LLNF 483
            ..|:
plant   485 YRNY 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	120/485 (25%)
CYP711A1	NP_565617.2	cytochrome_P450	75..515	CDD:425388	110/460 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D786853at2759
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.860