Protein Alignment Cyp9h1 and cyp17a2

DIOPT Version :10

• Sequence 1: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001099140.1
• Gene: cyp17a2 / 796487
• ZFINID: ZDB-GENE-100822-1
• Length: 495
• Species: Danio rerio
• Alignment Length: 528
• Identity: 131/528 - (24%)
• Similarity: 221/528 - (41%)
• Gaps: 104/528 - (19%)

  Fly     7 ALALFIILLV--LLYKWSVAKYDVFSERGV-SHEKPWPLIGNIPLKAMIGGMPVLKKMIELHTKH 68
            ||.|.::|||  ||             .|| |....:|.:..:||   :|.:..|:..:..|...
Zfish    12 ALLLLLLLLVRRLL-------------EGVGSSSVSFPCLPRLPL---LGSLLHLRSNLPPHLLF 60

  Fly    69 TG-----SPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNSMHNNIQESILSK--SLISLR 126
            |.     .|::|:||.......|.:..|::.:.::....|.....|   :...:|::  ..|:..
Zfish    61 TQLSSQYGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKM---VTTDLLTQGGKDIAFA 122

  Fly   127 D--GRWKEMRNILTPAFT----GSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFT 185
            |  ..||..|.::..:||    ||      :.:|:..:|....:.|:|:..:..|.:|.:  ...
Zfish   123 DYSPLWKNHRRLVHSSFTLFGEGS------NKLQTIVQEAADSLCEELQACRGQSSDLSV--VLM 179

  Fly   186 RFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYALFP-----------RLM 239
            |...:||..:.|.   :|::..|.|...:.|....| ..::.:..|..:||           ||.
Zfish   180 RAVTNVICRLVFS---SSYQPSDPELQTVIQYNDGI-VQTIARGGLVDIFPWLRIFPNKDLKRLK 240

  Fly   240 KV--LRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYS 302
            :.  :|.|:|..|.:::..||.....|          |::..|:..:|:......|
Zfish   241 ECVSIRDQLLYKKLLEHKKSLTPGEPR----------DLLDALLIGQQRGSGGADD--------- 286

  Fly   303 EFTADDLLAQCLLFFFAGFEIISSSL----CFLTHELCLNPTVQDRLYEEIISVHEELKG--QPL 361
             .|.|.:|......|.||.|..|::|    .||.|    :|.:|:|:..|:    :|..|  :|.
Zfish   287 -ITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLH----HPQLQERVQAEL----DECVGVDRPP 342

  Fly   362 TYDKLTKMKYLDMVVLEALRKWPPS-ISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHH 425
            .......:..||.|:.|.:|..|.| |.......||..|   .|.   |..||..:.:.::::||
Zfish   343 CLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSL---GGH---SVPKGTRVLVNMWAIHH 401

  Fly   426 DPENFEDPEFFNPERFAD--GHALESRVYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKL-LP 487
            ||::::.||.||||||.:  |.......::|||.|||.|:|..:|.:||...|.:.|..|.. .|
Zfish   402 DPKHWDQPEQFNPERFLEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSFSCP 466

  Fly   488 AKRTSRDL 495
            ::.:..||
Zfish   467 SEASLPDL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	CYP6-like	69..511	CDD:410679	114/463 (25%)
cyp17a2	NP_001099140.1	CYP17A1	67..489	CDD:410766	113/457 (25%)